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Protein or Target Summary

High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B

Gene ID8622
uniprotO95263
Gene NamePDE8B
Ensernbl IDENSP00000264917
FamilyBelongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
Sequence
MGCAPSIHVSQSGVIYCRDSDESSSPRQTTSVSQGPAAPLPGLFVQTDAADAIPPSRASGPPSVARVRRARTELGSGSSAGSAAPAATTSRGRRRHCCSSAEAETQTCYTSVKQVSSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEIIVIDHRQTQNFDAEAVCRSIRATNPSEHTVILAVVSRVSDDHEEASVLPLLHAGFNRRFMENSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERMMGYHKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRDSGDNSQTEPHSFRYKNRRKESIDVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLEILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPITINDVPPCISQLLDNEESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN8622PDE8BHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8BO95263
MOUSEPde8bPhosphodiesteraseA6YR19
MOUSEPde8bPhosphodiesteraseE9Q7S6
MOUSEPde8bHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8BE0CXQ1
MOUSEPde8bHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8BE0CY70
MOUSEPde8bHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8BF7CT85
MOUSE218461Pde8bPhosphodiesteraseE9PX38
MOUSE218461Pde8bPhosphodiesteraseQ8BI47
MOUSEPde8bUncharacterized proteinQ3U4Q2
MOUSEPde8bUncharacterized proteinQ3UUK9
MOUSEPde8bPhosphodiesteraseQ8BIA0
MOUSE218461Pde8bPhosphodiesteraseE9Q8J6
MOUSE218461Pde8bPhosphodiesteraseE9PYP0
MOUSEPde8bPhosphodiesteraseE9PUL4
MOUSEPde8bPhosphodiesteraseQ8CFW8
MOUSE218461Pde8bPhosphodiesteraseE9PXX4
MOUSEPde8bHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8BE9Q4S1
RAT309962Pde8bPhosphodiesteraseQ76KC5

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

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      Source: DataSourcesLicenses.xlsx
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