PDE5A

DescriptioncGMP-specific 3',5'-cyclic phosphodiesterase

Gene and Protein Information

Gene ID8654
Uniprot Accession IDs A0AV69 A8K2C4 O75026 O75887 Q86UI0 Q86V66 Q9Y6Z6
Ensembl ID ENSP00000347046
Symbol PDE5 CN5A PDE5 CGB-PDE
FamilyBelongs to the cyclic nucleotide phosphodiesterase family.
Sequence
MERAGPSFGQQRQQQQPQQQKQQQRDQDSVEAWLDDHWDFTFSYFVRKATREMVNAWFAERVHTIPVCKEGIRGHTESCSCPLQQSPRADNSAPGTPTRKISASEFDRPLRPIVVKDSEGTVSFLSDSEKKEQMPLTPPRFDHDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLVCEDSSNDKFLISRLFDVAEGSTLEEVSNNCIRLEWNKGIVGHVAALGEPLNIKDAYEDPRFNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIFIVDEDCSDSFSSVFHMECEELEKSSDTLTREHDANKINYMYAQYVKNTMEPLNIPDVSKDKRFPWTTENTGNVNQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKVKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQQEKMLINGESGQAKRN
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp461461PDE5Aphosphodiesterase 5A9598VGNC:2966OMA, EggNOG
Macaque705592PDE5Aphosphodiesterase 5A9544OMA, EggNOG
Mouse242202Pde5aphosphodiesterase 5A, cGMP-specific10090MGI:2651499OMA, EggNOG
Rat171115Pde5aphosphodiesterase 5A10116RGD:620995OMA, EggNOG
Dog403825PDE5Aphosphodiesterase 5A9615VGNC:44356OMA, EggNOG
Horse100072395PDE5Aphosphodiesterase 5A9796VGNC:21247OMA, EggNOG
Cow281972PDE5Aphosphodiesterase 5A9913VGNC:32678OMA, EggNOG
Pig397616PDE5Aphosphodiesterase 5A9823OMA, EggNOG
Opossum100018314PDE5Aphosphodiesterase 5A13616OMA, EggNOG
Platypus100081836PDE5Aphosphodiesterase 5A9258OMA, EggNOG

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source