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PDE5A
| Description | cGMP-specific 3',5'-cyclic phosphodiesterase |
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Gene and Protein Information
| Gene ID | 8654 |
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| Uniprot Accession IDs | A0AV69 A8K2C4 O75026 O75887 Q86UI0 Q86V66 Q9Y6Z6 |
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| Ensembl ID | ENSP00000347046 |
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| Symbol | PDE5 CN5A PDE5 CGB-PDE |
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| Family | Belongs to the cyclic nucleotide phosphodiesterase family. |
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| Sequence | MERAGPSFGQQRQQQQPQQQKQQQRDQDSVEAWLDDHWDFTFSYFVRKATREMVNAWFAERVHTIPVCKEGIRGHTESCSCPLQQSPRADNSAPGTPTRKISASEFDRPLRPIVVKDSEGTVSFLSDSEKKEQMPLTPPRFDHDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLVCEDSSNDKFLISRLFDVAEGSTLEEVSNNCIRLEWNKGIVGHVAALGEPLNIKDAYEDPRFNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIFIVDEDCSDSFSSVFHMECEELEKSSDTLTREHDANKINYMYAQYVKNTMEPLNIPDVSKDKRFPWTTENTGNVNQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKVKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQQEKMLINGESGQAKRN Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 461461 | PDE5A | phosphodiesterase 5A | 9598 | VGNC:2966 | OMA, EggNOG |
| Macaque | 705592 | PDE5A | phosphodiesterase 5A | 9544 | | OMA, EggNOG |
| Mouse | 242202 | Pde5a | phosphodiesterase 5A, cGMP-specific | 10090 | MGI:2651499 | OMA, EggNOG |
| Rat | 171115 | Pde5a | phosphodiesterase 5A | 10116 | RGD:620995 | OMA, EggNOG |
| Dog | 403825 | PDE5A | phosphodiesterase 5A | 9615 | VGNC:44356 | OMA, EggNOG |
| Horse | 100072395 | PDE5A | phosphodiesterase 5A | 9796 | VGNC:21247 | OMA, EggNOG |
| Cow | 281972 | PDE5A | phosphodiesterase 5A | 9913 | VGNC:32678 | OMA, EggNOG |
| Pig | 397616 | PDE5A | phosphodiesterase 5A | 9823 | | OMA, EggNOG |
| Opossum | 100018314 | PDE5A | phosphodiesterase 5A | 13616 | | OMA, EggNOG |
| Platypus | 100081836 | PDE5A | phosphodiesterase 5A | 9258 | | OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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