PDK1
| Description | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial |
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Gene and Protein Information
| Gene ID | 5163 |
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| Uniprot Accession IDs | B2R6T1 B7Z937 D3DPD8 E9PD65 Q308M4 |
| Ensembl ID | ENSP00000376352 |
| Symbol | PDHK1 |
| Family | Belongs to the PDK/BCKDK protein kinase family. |
| Sequence | MRLARLLRGAALAGPGPGLRAAGFSRSFSSDSGSSPASERGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRHNDVIPTMAQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 459743 | PDK1 | pyruvate dehydrogenase kinase 1 | 9598 | VGNC:6370 | OMA, EggNOG |
| Macaque | 697772 | PDK1 | pyruvate dehydrogenase kinase 1 | 9544 | OMA, EggNOG | |
| Mouse | 228026 | Pdk1 | pyruvate dehydrogenase kinase, isoenzyme 1 | 10090 | MGI:1926119 | Inparanoid, OMA, EggNOG |
| Rat | 116551 | Pdk1 | pyruvate dehydrogenase kinase 1 | 10116 | RGD:69427 | Inparanoid, OMA, EggNOG |
| Dog | 476828 | PDK1 | pyruvate dehydrogenase kinase 1 | 9615 | Inparanoid, OMA, EggNOG | |
| Horse | 100064091 | PDK1 | pyruvate dehydrogenase kinase 1 | 9796 | VGNC:21268 | Inparanoid, OMA, EggNOG |
| Cow | 528655 | PDK1 | pyruvate dehydrogenase kinase 1 | 9913 | VGNC:32703 | Inparanoid, OMA, EggNOG |
| Pig | 100286871 | PDK1 | pyruvate dehydrogenase kinase 1 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100617164 | PDK1 | pyruvate dehydrogenase kinase 1 | 13616 | OMA, EggNOG | |
| Platypus | 100084173 | PDK1 | pyruvate dehydrogenase kinase 1 | 9258 | Inparanoid, OMA, EggNOG | |
| Chicken | 425972 | PDK1 | pyruvate dehydrogenase kinase 1 | 9031 | CGNC:52628 | Inparanoid, OMA |
| Anole lizard | 100555492 | pdk1 | pyruvate dehydrogenase kinase 1 | 28377 | Inparanoid, OMA | |
| Xenopus | 100497838 | pdk1 | pyruvate dehydrogenase kinase 1 | 8364 | XB-GENE-483609 | Inparanoid, OMA |
| Zebrafish | 555840 | pdk1 | pyruvate dehydrogenase kinase, isozyme 1 | 7955 | ZDB-GENE-091204-402 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / protein kinase / [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
protein / transferase / [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
protein / kinase / [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
protein / protein kinase / [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
protein / transferase / [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
protein / kinase / [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
DTO Classes
protein / Kinase / Protein kinase / Atypical group / PDHK family / [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
protein / Kinase / Protein kinase / Atypical group / PDHK family / [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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