Your company account is blocked and you cannot place orders. If you have questions, please contact your company administrator.

PDCD1

DescriptionProgrammed cell death protein 1

Gene and Protein Information

Gene ID5133
Uniprot Accession IDs Q15116 O00517 Q8IX89 Protein PD-1
Ensembl ID ENSP00000335062
Symbol PD1 PD1 PD-1 CD279 SLEB2 hPD-1 hPD-l hSLE1
Sequence
MQIPQAPWPVVWAVLQLGWRPGWFLDSPDRPWNPPTFSPALLVVTEGDNATFTCSFSNTSESFVLNWYRMSPSNQTDKLAAFPEDRSQPGQDCRFRVTQLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIKESLRAELRVTERRAEVPTAHPSPSPRPAGQFQTLVVGVVGGLLGSLVLLVWVLAVICSRAARGTIGARRTGQPLKEDPSAVPVFSVDYGELDFQWREKTPEPPVPCVPEQTEYATIVFPSGMGTSSPARRGSADGPRSAQPLRPEDGHCSWPL
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque100135775PDCD1programmed cell death 19544Inparanoid, OMA, EggNOG
Mouse18566Pdcd1programmed cell death 110090MGI:104879Inparanoid, OMA, EggNOG
Rat301626Pdcd1programmed cell death 110116RGD:1311658OMA, EggNOG
Dog486213PDCD1programmed cell death 19615VGNC:44334Inparanoid, OMA, EggNOG
Horse100067948PDCD1programmed cell death 19796VGNC:21226Inparanoid, OMA, EggNOG
Cow613842PDCD1programmed cell death 19913VGNC:32657Inparanoid, OMA, EggNOG

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

The page will load shortly, Thanks for your patience!
NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      Bibliography

      1.Lindqvist, A K AK and 14 more authors. 2000-03 A susceptibility locus for human systemic lupus erythematosus (hSLE1) on chromosome 2q. [PMID:10677248]
      2.Gaffney, P M PM and 14 more authors. 2000-02 Genome screening in human systemic lupus erythematosus: results from a second Minnesota cohort and combined analyses of 187 sib-pair families. [PMID:10677315]
      3.Iwai, Yoshiko Y and 5 more authors. 2002-10-01 Microanatomical localization of PD-1 in human tonsils. [PMID:12095712]
      4.Prokunina, Ludmila L and 23 more authors. 2002-12 A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. [PMID:12402038]
      5.Strausberg, Robert L RL and 83 more authors. 2002-12-24 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. [PMID:12477932]
      6.Bennett, Frann F and 11 more authors. 2003-01-15 Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses. [PMID:12517932]
      7.Wang, Shengdian S and 5 more authors. 2003-05-05 Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction. [PMID:12719480]
      8.Youngnak, Pornpan P and 10 more authors. 2003-08-01 Differential binding properties of B7-H1 and B7-DC to programmed death-1. [PMID:12893276]
      9.Ishida, Y Y, Agata, Y Y, Shibahara, K K and Honjo, T T. 1992-11 Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. [PMID:1396582]
      10.Nielsen, C C, Hansen, D D, Husby, S S, Jacobsen, B B BB and Lillevang, S T ST. 2003-12 Association of a putative regulatory polymorphism in the PD-1 gene with susceptibility to type 1 diabetes. [PMID:14617032]