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Protein or Target Summary

cAMP-specific 3',5'-cyclic phosphodiesterase 4A

Gene ID5141
uniprotP27815
Gene NamePDE4A
Ensernbl IDENSP00000370078
FamilyBelongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
Sequence
MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAERERQPHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGSGGAGGGSSRRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACAGTFGEDTSALPAPGGGGSGGDPT
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN5141PDE4AcAMP-specific 3',5'-cyclic phosphodiesterase 4AP27815
MOUSE18577Pde4aPhosphodiesteraseQ3TUD0
MOUSEPde4aCyclic AMP specific phosphodiesterase PDE4A5AO70285
MOUSEPde4aPhosphodiesteraseC9K100
MOUSEPde4aPde4a proteinQ80UU8
MOUSE18577Pde4aPhosphodiesteraseB2RTL2
MOUSE18577Pde4acAMP-specific 3',5'-cyclic phosphodiesterase 4AO89084
RATPde4aPhosphodiesteraseF1M8I9
RAT25638Pde4acAMP-specific 3',5'-cyclic phosphodiesterase 4AP54748

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
      Source: DataSourcesLicenses.xlsx
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