ELANE

Description	Neutrophil elastase

Gene and Protein Information

Gene ID	1991
Uniprot Accession IDs	P09649 Q6B0D9 Q6LDP5
Ensembl ID	ENSP00000466090
Symbol	ELA2 GE NE HLE HNE ELA2 SCN1 PMN-E
Family	Belongs to the peptidase S1 family. Elastase subfamily.
Sequence	MTLGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCPHPRDPDPASRTH

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	749897	ELANE	elastase, neutrophil expressed	9598		OMA, EggNOG
Macaque	106992354	ELANE	elastase, neutrophil expressed	9544		OMA, EggNOG
Mouse	50701	Elane	elastase, neutrophil expressed	10090	MGI:2679229	Inparanoid, OMA, EggNOG
Rat	299606	Elane	elastase, neutrophil expressed	10116	RGD:1307968	Inparanoid, OMA, EggNOG
Dog	442980	ELANE	elastase, neutrophil expressed	9615		Inparanoid, OMA, EggNOG
Cow	100126050	ELANE	elastase, neutrophil expressed	9913	VGNC:28423	Inparanoid, OMA, EggNOG
Pig	100522182	ELANE	elastase, neutrophil expressed	9823		OMA, EggNOG
Opossum	100030465	LOC100030465	neutrophil elastase	13616		Inparanoid, OMA, EggNOG
Xenopus	448597	prtn3	proteinase 3	8364	XB-GENE-5805214	OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    serine protease    /    Neutrophil elastase
protein    /    protease    /    Neutrophil elastase
protein    /    hydrolase    /    Neutrophil elastase

DTO Classes
protein / Enzyme / Protease / Serine protease / Neutrophil elastase

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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