PCSK4

DescriptionProprotein convertase subtilisin/kexin type 4

Gene and Protein Information

Gene ID54760
Uniprot Accession IDs Q8IY88 Q9UF79
Ensembl ID ENSP00000300954
Symbol PC4 PC4 SPC5
FamilyBelongs to the peptidase S8 family. Furin subfamily.
Sequence
MRPAPIALWLRLVLALALVRPRAVGWAPVRAPIYVSSWAVQVSQGNREVERLARKFGFVNLGPIFPDGQYFHLRHRGVVQQSLTPHWGHRLHLKKNPKVQWFQQQTLQRRVKRSVVVPTDPWFSKQWYMNSEAQPDLSILQAWSQGLSGQGIVVSVLDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPSKENRHGTRCAGEVAAMANNGFCGVGVAFNARIGGVRMLDGTITDVIEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGILTREAFRRGVTKGRGGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTQQGRVPWYSEACASTLTTTYSSGVATDPQIVTTDLHHGCTDQHTGTSASAPLAAGMIALALEANPFLTWRDMQHLVVRASKPAHLQAEDWRTNGVGRQVSHHYGYGLLDAGLLVDTARTWLPTQPQRKCAVRVQSRPTPILPLIYIRENVSACAGLHNSIRSLEHVQAQLTLSYSRRGDLEISLTSPMGTRSTLVAIRPLDVSTEGYNNWVFMSTHFWDENPQGVWTLGLENKGYYFNTGTLYRYTLLLYGTAEDMTARPTGPQVTSSACVQRDTEGLCQACDGPAYILGQLCLAYCPPRFFNHTRLVTAGPGHTAAPALRVCSSCHASCYTCRGGSPRDCTSCPPSSTLDQQQGSCMGPTTPDSRPRLRAAACPHHRCPASAMVLSLLAVTLGGPVLCGMSMDLPLYAWLSRARATPTKPQVWLPAGT
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp749996PCSK4proprotein convertase subtilisin/kexin type 49598VGNC:7541Inparanoid, OMA
Macaque707567PCSK4proprotein convertase subtilisin/kexin type 49544Inparanoid, OMA, EggNOG
Mouse18551Pcsk4proprotein convertase subtilisin/kexin type 410090MGI:97514Inparanoid, OMA, EggNOG
Rat171085Pcsk4proprotein convertase subtilisin/kexin type 410116RGD:620325Inparanoid, OMA, EggNOG
Dog485083PCSK4proprotein convertase subtilisin/kexin type 49615VGNC:44323Inparanoid, OMA
Pig100626523PCSK4proprotein convertase subtilisin/kexin type 49823Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    serine protease    /    Proprotein convertase subtilisin/kexin type 4
DTO Classes
protein    /    Enzyme    /    Protease    /    Serine protease    /    Proprotein convertase subtilisin/kexin type 4

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source