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CD274

DescriptionProgrammed cell death 1 ligand 1

Gene and Protein Information

Gene ID29126
Uniprot Accession IDs Q9NZQ7 B2RBA2 B4DU27 Q14CJ2 Q2V8D5 Q66RK1 Q6WEX4 Q9NUZ5 PD-L1
Ensembl ID ENSP00000370989
Symbol B7H1 PDCD1L1 PDCD1LG1 PDL1 B7-H B7H1 PDL1 PD-L1 PDCD1L1 PDCD1LG1
FamilyBelongs to the immunoglobulin superfamily. BTN/MOG family.
Sequence
MRIFAVFIFMTYWHLLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTHLVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQSDTHLEET
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp464981CD274CD274 molecule9598VGNC:4652OMA, EggNOG
Macaque716043CD274CD274 molecule9544Inparanoid, OMA
Mouse60533Cd274CD274 antigen10090MGI:1926446Inparanoid, OMA, EggNOG
Rat499342Cd274CD274 molecule10116RGD:1566211Inparanoid, OMA, EggNOG
Dog484186CD274CD274 molecule9615VGNC:38942Inparanoid, OMA, EggNOG
Horse100051703CD274CD274 molecule9796VGNC:16256Inparanoid, OMA, EggNOG
Cow533834CD274CD274 molecule9913VGNC:27019OMA, EggNOG
Pig574058CD274CD274 molecule9823OMA, EggNOG
Opossum100018006CD274CD274 molecule13616Inparanoid, OMA, EggNOG
Platypus100074433CD274CD274 molecule9258Inparanoid, OMA, EggNOG
Chicken427224CD274CD274 molecule9031CGNC:11177Inparanoid, EggNOG
Xenopuscd274CD274 molecule8364XB-GENE-921387Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    receptor    /    immunoglobulin receptor superfamily    /    Programmed cell death 1 ligand 1
protein    /    receptor    /    defense/immunity protein    /    Programmed cell death 1 ligand 1
protein    /    receptor    /    membrane-bound signaling molecule    /    Programmed cell death 1 ligand 1
protein    /    receptor    /    cytokine receptor    /    Programmed cell death 1 ligand 1
DTO Classes
protein    /    Receptor    /    Cytokine receptor    /    Immunoglobulin receptor superfamily    /    Programmed cell death 1 ligand 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

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NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

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      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

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