CD274
| Description | Programmed cell death 1 ligand 1 |
|---|
Gene and Protein Information
| Gene ID | 29126 |
|---|---|
| Uniprot Accession IDs | B2RBA2 B4DU27 Q14CJ2 Q2V8D5 Q66RK1 Q6WEX4 Q9NUZ5 PD-L1 |
| Ensembl ID | ENSP00000370989 |
| Symbol | B7H1 PDCD1L1 PDCD1LG1 PDL1 B7-H B7H1 PDL1 PD-L1 PDCD1L1 PDCD1LG1 |
| Family | Belongs to the immunoglobulin superfamily. BTN/MOG family. |
| Sequence | MRIFAVFIFMTYWHLLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTHLVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQSDTHLEET |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 464981 | CD274 | CD274 molecule | 9598 | VGNC:4652 | OMA, EggNOG |
| Macaque | 716043 | CD274 | CD274 molecule | 9544 | Inparanoid, OMA | |
| Mouse | 60533 | Cd274 | CD274 antigen | 10090 | MGI:1926446 | Inparanoid, OMA, EggNOG |
| Rat | 499342 | Cd274 | CD274 molecule | 10116 | RGD:1566211 | Inparanoid, OMA, EggNOG |
| Dog | 484186 | CD274 | CD274 molecule | 9615 | VGNC:38942 | Inparanoid, OMA, EggNOG |
| Horse | 100051703 | CD274 | CD274 molecule | 9796 | VGNC:16256 | Inparanoid, OMA, EggNOG |
| Cow | 533834 | CD274 | CD274 molecule | 9913 | VGNC:27019 | OMA, EggNOG |
| Pig | 574058 | CD274 | CD274 molecule | 9823 | OMA, EggNOG | |
| Opossum | 100018006 | CD274 | CD274 molecule | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | 100074433 | CD274 | CD274 molecule | 9258 | Inparanoid, OMA, EggNOG | |
| Chicken | 427224 | CD274 | CD274 molecule | 9031 | CGNC:11177 | Inparanoid, EggNOG |
| Xenopus | cd274 | CD274 molecule | 8364 | XB-GENE-921387 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / receptor / immunoglobulin receptor superfamily / Programmed cell death 1 ligand 1
protein / receptor / defense/immunity protein / Programmed cell death 1 ligand 1
protein / receptor / membrane-bound signaling molecule / Programmed cell death 1 ligand 1
protein / receptor / cytokine receptor / Programmed cell death 1 ligand 1
protein / receptor / immunoglobulin receptor superfamily / Programmed cell death 1 ligand 1
protein / receptor / defense/immunity protein / Programmed cell death 1 ligand 1
protein / receptor / membrane-bound signaling molecule / Programmed cell death 1 ligand 1
protein / receptor / cytokine receptor / Programmed cell death 1 ligand 1
DTO Classes
protein / Receptor / Cytokine receptor / Immunoglobulin receptor superfamily / Programmed cell death 1 ligand 1
protein / Receptor / Cytokine receptor / Immunoglobulin receptor superfamily / Programmed cell death 1 ligand 1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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