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PCSK9
| Description | Proprotein convertase subtilisin/kexin type 9 |
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Gene and Protein Information
| Gene ID | 255738 |
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| Uniprot Accession IDs | Q8NBP7 A8T640 C0JYY9 Q5PSM5 Q5SZQ2 |
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| Ensembl ID | ENSP00000303208 |
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| Symbol | NARC1 FH3 PC9 NARC1 LDLCQ1 NARC-1 HCHOLA3 |
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| Family | Belongs to the peptidase S8 family. |
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| Sequence | MGTVSSRRSWWPLPLLLLLLLLLGPAGARAQEDEDGDYEELVLALRSEEDGLAEAPEHGTTATFHRCAKDPWRLPGTYVVVLKEETHLSQSERTARRLQAQAARRGYLTKILHVFHGLLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQSIPWNLERITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGASMRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVLNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHGAGWQLFCRTVWSAHSGPTRMATAVARCAPDEELLSCSSFSRSGKRRGERMEAQGGKLVCRAHNAFGGEGVYAIARCCLLPQANCSVHTAPPAEASMGTRVHCHQQGHVLTGCSSHWEVEDLGTHKPPVLRPRGQPNQCVGHREASIHASCCHAPGLECKVKEHGIPAPQEQVTVACEEGWTLTGCSALPGTSHVLGAYAVDNTCVVRSRDVSTTGSTSEGAVTAVAICCRSRHLAQASQELQ Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 456880 | PCSK9 | proprotein convertase subtilisin/kexin type 9 | 9598 | VGNC:9382 | Inparanoid, OMA, EggNOG |
| Macaque | 717147 | PCSK9 | proprotein convertase subtilisin/kexin type 9 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 100102 | Pcsk9 | proprotein convertase subtilisin/kexin type 9 | 10090 | MGI:2140260 | Inparanoid, OMA, EggNOG |
| Rat | 298296 | Pcsk9 | proprotein convertase subtilisin/kexin type 9 | 10116 | RGD:728909 | Inparanoid, OMA, EggNOG |
| Horse | 100147049 | PCSK9 | proprotein convertase subtilisin/kexin type 9 | 9796 | VGNC:50739 | Inparanoid, OMA, EggNOG |
| Pig | 100620501 | PCSK9 | proprotein convertase subtilisin/kexin type 9 | 9823 | | OMA, EggNOG |
| Opossum | | PCSK9 | proprotein convertase subtilisin/kexin type 9 [Source:HGNC Symbol;Acc:HGNC:20001] | 13616 | | Inparanoid, OMA, EggNOG |
| Anole lizard | 100564252 | pcsk9 | proprotein convertase subtilisin/kexin type 9 | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | 100484989 | pcsk9 | proprotein convertase subtilisin/kexin type 9 | 8364 | XB-GENE-998025 | Inparanoid, OMA, EggNOG |
| Zebrafish | 100150316 | pcsk9 | proprotein convertase subtilisin/kexin type 9 | 7955 | ZDB-GENE-060927-1 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes protein /
serine protease / Proprotein convertase subtilisin/kexin type 9
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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