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Targets(Human)
PTGS2

PTGS2

Description	Prostaglandin G/H synthase 2

Gene and Protein Information

Gene ID	5743
Uniprot Accession IDs	A8K802 Q16876
Ensembl ID	ENSP00000356438
Symbol	COX2 COX2 COX-2 PHS-2 PGG/HS PGHS-2 hCox-2 GRIPGHS
Family	Belongs to the prostaglandin G/H synthase family.
Sequence	MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	469616	PTGS2	prostaglandin-endoperoxide synthase 2	9598	VGNC:6970	OMA, EggNOG
Macaque	716671	PTGS2	prostaglandin-endoperoxide synthase 2	9544		Inparanoid, OMA, EggNOG
Mouse	19225	Ptgs2	prostaglandin-endoperoxide synthase 2	10090	MGI:97798	Inparanoid, OMA, EggNOG
Rat	29527	Ptgs2	prostaglandin-endoperoxide synthase 2	10116	RGD:620349	Inparanoid, OMA, EggNOG
Dog	442942	PTGS2	prostaglandin-endoperoxide synthase 2	9615	VGNC:45152	OMA, EggNOG
Horse	791253	PTGS2	prostaglandin-endoperoxide synthase 2	9796	VGNC:21997	Inparanoid, OMA, EggNOG
Cow	282023	PTGS2	prostaglandin-endoperoxide synthase 2	9913	VGNC:33512	Inparanoid, OMA, EggNOG
Opossum	100024802	PTGS2	prostaglandin-endoperoxide synthase 2	13616		Inparanoid, OMA, EggNOG
Platypus	100086096	PTGS2	prostaglandin-endoperoxide synthase 2	9258		Inparanoid, OMA, EggNOG
Anole lizard	100560130	ptgs2	prostaglandin-endoperoxide synthase 2	28377		Inparanoid, OMA
Xenopus	595089	ptgs2	prostaglandin-endoperoxide synthase 2	8364	XB-GENE-482133	Inparanoid, OMA
Zebrafish	559020	ptgs2b	prostaglandin-endoperoxide synthase 2b	7955	ZDB-GENE-041014-323	Inparanoid, OMA

Protein Classes

PANTHER Classes
protein / oxidoreductase / oxygenase / Prostaglandin G/H synthase 2

DTO Classes
protein / Enzyme / Oxidoreductase / Oxygenase / Prostaglandin G/H synthase 2

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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