PKN2

DescriptionSerine/threonine-protein kinase N2

Gene and Protein Information

Gene ID5586
Uniprot Accession IDs B4DQ21 B4DTP5 B4DVG1 D3DT24 Q08AF4 Q9H1W4
Ensembl ID ENSP00000359552
Symbol PRK2 PRKCL2 PAK2 PRK2 STK7 Pak-2 PRKCL2 PRO2042
FamilyBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Sequence
MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKELKIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPRTPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVAASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPVPTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPGQDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYIADWC
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp456998PKN2protein kinase N29598VGNC:1457OMA, EggNOG
Macaque693505PKN2protein kinase N29544Inparanoid, OMA, EggNOG
Mouse109333Pkn2protein kinase N210090MGI:109211Inparanoid, OMA, EggNOG
Rat207122Pkn2protein kinase N210116RGD:620146Inparanoid, OMA, EggNOG
Dog490174PKN2protein kinase N29615VGNC:44612Inparanoid, OMA, EggNOG
Horse100052266PKN2protein kinase N29796VGNC:21498Inparanoid, OMA, EggNOG
Cow519754PKN2protein kinase N29913VGNC:32946Inparanoid, OMA, EggNOG
Pig100154766PKN2protein kinase N29823Inparanoid, OMA, EggNOG
Opossum100027775PKN2protein kinase N213616Inparanoid, OMA, EggNOG
PlatypusPKN2protein kinase N2 [Source:HGNC Symbol;Acc:HGNC:9406]9258OMA, EggNOG
Anole lizard100555795pkn2protein kinase N228377Inparanoid, OMA
Zebrafish571965pkn2protein kinase N27955ZDB-GENE-061207-42Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    calcium-binding protein    /    non-receptor serine/threonine protein kinase    /    Serine/threonine-protein kinase n2
protein    /    calcium-binding protein    /    transfer/carrier protein    /    Serine/threonine-protein kinase n2
protein    /    calcium-binding protein    /    protein kinase    /    Serine/threonine-protein kinase n2
protein    /    calcium-binding protein    /    calmodulin    /    Serine/threonine-protein kinase n2
protein    /    calcium-binding protein    /    annexin    /    Serine/threonine-protein kinase n2
protein    /    calcium-binding protein    /    transferase    /    Serine/threonine-protein kinase n2
protein    /    calcium-binding protein    /    kinase    /    Serine/threonine-protein kinase n2
DTO Classes
protein    /    Kinase    /    Protein kinase    /    AGC group    /    PKN family    /    Serine/threonine-protein kinase n2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source