PIK3C3

DescriptionPhosphatidylinositol 3-kinase catalytic subunit type 3

Gene and Protein Information

Gene ID5289
Uniprot Accession IDs Q15134 PI3-kinase type 3
Ensembl ID ENSP00000262039
Symbol VPS34 VPS34 Vps34 hVps34
FamilyBelongs to the PI3/PI4-kinase family.
Sequence
MGEAEKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVFAEGKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGKAVPVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTKTPGRTSSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKEYGIVYYEKDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLEPTKKDSQSSVSENVSNSGINSAEIDSSQIITSPLPSVSSPPPASKTKEVPDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK
Show more
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp455385PIK3C3phosphatidylinositol 3-kinase catalytic subunit type 39598VGNC:7328OMA, EggNOG
Macaque693918PIK3C3phosphatidylinositol 3-kinase catalytic subunit type 39544Inparanoid, OMA, EggNOG
Mouse225326Pik3c3phosphatidylinositol 3-kinase catalytic subunit type 310090MGI:2445019Inparanoid, OMA, EggNOG
Rat65052Pik3c3phosphatidylinositol 3-kinase, catalytic subunit type 310116RGD:620899Inparanoid, OMA, EggNOG
Dog490477PIK3C3phosphatidylinositol 3-kinase catalytic subunit type 39615VGNC:44554Inparanoid, OMA, EggNOG
Horse100053039PIK3C3phosphatidylinositol 3-kinase catalytic subunit type 39796VGNC:21445Inparanoid, OMA, EggNOG
Cow534815PIK3C3phosphatidylinositol 3-kinase catalytic subunit type 39913VGNC:32888Inparanoid, OMA, EggNOG
Pig503700PIK3C3phosphatidylinositol 3-kinase catalytic subunit type 39823Inparanoid, OMA, EggNOG
Opossum100011397PIK3C3phosphatidylinositol 3-kinase catalytic subunit type 313616Inparanoid, OMA, EggNOG
Platypus100076306PIK3C3phosphatidylinositol 3-kinase catalytic subunit type 39258Inparanoid, OMA, EggNOG
Anole lizard100552043pik3c3phosphatidylinositol 3-kinase catalytic subunit type 328377Inparanoid, OMA, EggNOG
Xenopus100485933pik3c3phosphatidylinositol 3-kinase catalytic subunit type 38364XB-GENE-6085226Inparanoid, OMA, EggNOG
Zebrafish548346pik3c3phosphatidylinositol 3-kinase, catalytic subunit type 37955ZDB-GENE-050410-13Inparanoid, OMA, EggNOG
C. elegans172280vps-34Phosphatidylinositol 3-kinase catalytic subunit type 36239Inparanoid, OMA, EggNOG
Fruitfly37733Pi3K59FPhosphotidylinositol 3 kinase 59F7227FBgn0015277Inparanoid, EggNOG
S.cerevisiae850941VPS34phosphatidylinositol 3-kinase VPS344932S000004230Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transferase    /    Phosphatidylinositol 3-kinase catalytic subunit type 3
protein    /    kinase    /    Phosphatidylinositol 3-kinase catalytic subunit type 3
DTO Classes
protein    /    Kinase    /    Non-protein kinase    /    Lipid kinase    /    PI3/PI4 kinase family    /    Phosphatidylinositol 3-kinase catalytic subunit type 3

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source