SLC8B1

DescriptionMitochondrial sodium/calcium exchanger protein

Gene and Protein Information

Gene ID80024
Uniprot Accession IDs A6NP50 Q4KMS9 Q6J4K1 Q9H6I8
Ensembl ID ENSP00000447091
Symbol NCKX6 NCLX SLC24A6 NCLX NCKX6 SLC24A6
FamilyBelongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
Sequence
MAGRRLNLRWALSVLCVLLMAETVSGTRGSSTGAHISPQFPASGVNQTPVVDCRKVCGLNVSDRCDFIRTNPDCHSDGGYLDYLEGIFCHFPPSLLPLAVTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSALVAFSDPHTAGLALGALFGAGVLVTTVVAGGITILHPFMAASRPFFRDIVFYMVAVFLTFLMLFRGRVTLAWALGYLGLYVFYVVTVILCTWIYQRQRRGSLFCPMPVTPEILSDSEEDRVSSNTNSYDYGDEYRPLFFYQETTAQILVRALNPLDYMKWRRKSAYWKALKVFKLPVEFLLLLTVPVVDPDKDDQNWKRPLNCLHLVISPLVVVLTLQSGTYGVYEIGGLVPVWVVVVIAGTALASVTFFATSDSQPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQISRSHTEVKLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQLSRVYGFCLLLFYLNFLVVALLTEFGVIHLKSM
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp452406SLC8B1solute carrier family 8 member B19598VGNC:8549OMA, EggNOG
Mouse170756Slc8b1solute carrier family 8 (sodium/lithium/calcium exchanger), member B110090MGI:2180781Inparanoid, OMA, EggNOG
Rat498185Slc8b1solute carrier family 8 member B110116RGD:1565818Inparanoid, OMA, EggNOG
Dog486280SLC8B1solute carrier family 8 member B19615VGNC:46483OMA, EggNOG
Horse100056481SLC8B1solute carrier family 8 member B19796VGNC:23276OMA, EggNOG
Cow508887SLC8B1solute carrier family 8 member B19913VGNC:34938OMA, EggNOG
Pig100157056SLC8B1solute carrier family 8 member B19823OMA, EggNOG
OpossumSLC8B1solute carrier family 8 member B1 [Source:HGNC Symbol;Acc:HGNC:26175]13616OMA, EggNOG
Chicken417032SLC8B1solute carrier family 8 member B19031CGNC:6317Inparanoid, OMA, EggNOG
Anole lizard100560874slc8b1solute carrier family 8 member B128377OMA, EggNOG
Xenopusslc8b1solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 [Source:Xenbase;Acc:XB-GENE-957176]8364OMA, EggNOG
C. elegans182576ncx-9Mitochondrial sodium/calcium exchanger protein6239OMA, EggNOG
C. elegans190821ncx-10Na/Ca eXchangers6239Inparanoid, OMA
S.cerevisiae851321YDL206Whypothetical protein4932S000002365Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    transporter    /    cation transporter    /    Mitochondrial sodium/calcium exchanger protein
DTO Classes
protein    /    Transporter    /    SLC superfamily of solute carriers    /    SLC24 family of sodium/potassium/calcium exchangers    /    Mitochondrial sodium/calcium exchanger protein

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography