MME

DescriptionNeprilysin

Gene and Protein Information

Gene ID4311
Uniprot Accession IDs A8K6U6 D3DNJ9 Q3MIX4
Ensembl ID ENSP00000418525
Symbol EPN NEP SFE CD10 CALLA CMT2T SCA43
FamilyBelongs to the peptidase M13 family.
Sequence
MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp460792MMEmembrane metalloendopeptidase9598VGNC:14231OMA, EggNOG
Macaque707667MMEmembrane metalloendopeptidase9544Inparanoid, OMA, EggNOG
Mouse17380Mmemembrane metallo endopeptidase10090MGI:97004Inparanoid, OMA, EggNOG
Rat24590Mmemembrane metallo-endopeptidase10116RGD:3098Inparanoid, OMA, EggNOG
Dog477120MMEmembrane metalloendopeptidase9615VGNC:43271Inparanoid, OMA, EggNOG
Horse100053541MMEmembrane metalloendopeptidase9796VGNC:20220Inparanoid, OMA, EggNOG
Cow536741MMEmembrane metalloendopeptidase9913VGNC:31514Inparanoid, OMA, EggNOG
Pig100511536MMEmembrane metalloendopeptidase9823OMA, EggNOG
Opossum100012497MMEmembrane metalloendopeptidase13616Inparanoid, OMA, EggNOG
Chicken425031MMEmembrane metalloendopeptidase9031CGNC:7860Inparanoid, OMA
Anole lizard100558527mmemembrane metalloendopeptidase28377Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    metalloprotease    /    Neprilysin
DTO Classes
protein    /    Enzyme    /    Protease    /    Metalloprotease    /    Neprilysin

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source