RIPK1

DescriptionReceptor-interacting serine/threonine-protein kinase 1

Gene and Protein Information

Gene ID8737
Uniprot Accession IDs A0AV89 B2RAG1 B4E3F9 Q13180 Q59H33
Ensembl ID ENSP00000259808
Symbol RIP RIP1 RIP RIP1 IMD57 RIP-1
FamilyBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
Sequence
MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp462397RIPK1receptor interacting serine/threonine kinase 19598VGNC:11209OMA, EggNOG
Macaque708013RIPK1receptor interacting serine/threonine kinase 19544Inparanoid, OMA, EggNOG
Mouse19766Ripk1receptor (TNFRSF)-interacting serine-threonine kinase 110090MGI:108212Inparanoid, OMA, EggNOG
Rat306886Ripk1receptor interacting serine/threonine kinase 110116RGD:1310158Inparanoid, OMA, EggNOG
Dog102152063RIPK1receptor interacting serine/threonine kinase 19615VGNC:45594Inparanoid, OMA, EggNOG
Horse100058015RIPK1receptor interacting serine/threonine kinase 19796VGNC:22398Inparanoid, OMA, EggNOG
Cow504727RIPK1receptor interacting serine/threonine kinase 19913VGNC:33981Inparanoid, OMA, EggNOG
Pig100524751RIPK1receptor interacting serine/threonine kinase 19823Inparanoid, OMA, EggNOG
Opossum100028597RIPK1receptor interacting serine/threonine kinase 113616Inparanoid, OMA, EggNOG
Platypus100079746RIPK1receptor interacting serine/threonine kinase 19258Inparanoid, OMA, EggNOG
Chicken378921RIPK1receptor interacting serine/threonine kinase 19031CGNC:9719Inparanoid, OMA
Anole lizard100556206ripk1receptor interacting serine/threonine kinase 128377Inparanoid, OMA, EggNOG
Xenopus779958ripk1receptor interacting serine/threonine kinase 18364XB-GENE-1012365Inparanoid, OMA, EggNOG
Zebrafish567460ripk1lreceptor (TNFRSF)-interacting serine-threonine kinase 1, like7955ZDB-GENE-070705-132Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    RIPK family    /    Receptor-interacting serine/threonine-protein kinase 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source