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Protein or Target Summary

Interferon-induced, double-stranded RNA-activated protein kinase

Gene ID5610
uniprotP19525
Gene NameEIF2AK2
Ensernbl IDENSP00000233057
FamilyBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.
Sequence
MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQCASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSGSFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAKRSLAPRFDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWKKSPEKNERHTC
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN5610EIF2AK2Interferon-induced, double-stranded RNA-activated protein kinaseP19525
MOUSE19106Eif2ak2Interferon-induced, double-stranded RNA-activated protein kinaseQ03963
MOUSEEif2ak2Protein kinaseQ78E06
MOUSEEif2ak2Eif2ak2 proteinQ91YN2
RAT54287Eif2ak2Interferon-induced, double-stranded RNA-activated protein kinaseQ63184
RAT54287Eif2ak2Interferon-induced, double-stranded RNA-activated protein kinaseM0RDJ3

Protein Classes

PANTHER Classes
protein    /    non-receptor serine/threonine protein kinase    /    Interferon-induced, double-stranded rna-activated protein kinase
protein    /    protein kinase    /    Interferon-induced, double-stranded rna-activated protein kinase
protein    /    transferase    /    Interferon-induced, double-stranded rna-activated protein kinase
protein    /    kinase    /    Interferon-induced, double-stranded rna-activated protein kinase
DTO Classes
protein    /    Kinase    /    Protein kinase    /    Other group    /    PEK family    /    Interferon-induced, double-stranded rna-activated protein kinase

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source