| Description | Eukaryotic translation initiation factor 2-alpha kinase 3 |
|---|
Gene and Protein Information
| Gene ID | 9451 |
|---|---|
| Uniprot Accession IDs | A0AVH1 A0AVH2 B2RCU9 O95846 Q53QY0 Q53SB1 |
| Ensembl ID | ENSP00000307235 |
| Symbol | PEK PERK PEK WRS PERK |
| Family | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily. |
| Sequence | MERAISPGLLVRALLLLLLLLGLAARTVAAGRARGLPAPTAEAAFGLGAAAAPTSATRVPAAGAVAAAEVTVEDAEALPAAAGEQEPRGPEPDDETELRPRGRSLVIISTLDGRIAALDPENHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGALFQWDQDRESMETVPFTVESLLESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDSDEMEQEEDILLLQRTQKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTFKPNENTEESKIISDVEEQEAAIMDIVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLLKDGKVIPISLFDDTSYTSNDDVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPSSPKALESVTNENAIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYYLPYYKRERNKRSTQITVRFLDNPHYNKNIRKKDPVLLLHWWKEIVATILFCIIATTFIVRRLFHPHPHRQRKESETQCQTENKYDSVSGEANDSSWNDIKNSGYISRYLTDFEPIQCLGRGGFGVVFEAKNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEAPPEKWQEKMDEIWLKDESTDWPLSSPSPMDAPSVKIRRMDPFATKEHIEIIAPSPQRSRSFSVGISCDQTSSSESQFSPLEFSGMDHEDISESVDAAYNLQDSCLTDCDVEDGTMDGNDEGHSFELCPSEASPYVRSRERTSSSIVFEDSGCDNASSKEEPKTNRLHIGNHCANKLTAFKPTSSKSSSEATLSISPPRPTTLSLDLTKNTTEKLQPSSPKVYLYIQMQLCRKENLKDWMNGRCTIEERERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQDEEEQTVLTPMPAYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCEYVMVQDMLSPSPMERPEAINIIENAVFEDLDFPGKTVLRQRSRSLSSSGTKHSRQSNNSHSPLPSN Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 459388 | EIF2AK3 | eukaryotic translation initiation factor 2 alpha kinase 3 | 9598 | VGNC:237 | OMA, EggNOG |
| Macaque | 699575 | EIF2AK3 | eukaryotic translation initiation factor 2 alpha kinase 3 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 13666 | Eif2ak3 | eukaryotic translation initiation factor 2 alpha kinase 3 | 10090 | MGI:1341830 | Inparanoid, OMA, EggNOG |
| Rat | 29702 | Eif2ak3 | eukaryotic translation initiation factor 2 alpha kinase 3 | 10116 | RGD:70884 | Inparanoid, OMA, EggNOG |
| Dog | 475756 | EIF2AK3 | eukaryotic translation initiation factor 2 alpha kinase 3 | 9615 | VGNC:40258 | Inparanoid, OMA, EggNOG |
| Horse | 100066488 | EIF2AK3 | eukaryotic translation initiation factor 2 alpha kinase 3 | 9796 | VGNC:17479 | Inparanoid, OMA, EggNOG |
| Cow | 535820 | EIF2AK3 | eukaryotic translation initiation factor 2 alpha kinase 3 | 9913 | VGNC:28382 | Inparanoid, OMA, EggNOG |
| Pig | 100513348 | EIF2AK3 | eukaryotic translation initiation factor 2 alpha kinase 3 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100029557 | EIF2AK3 | eukaryotic translation initiation factor 2 alpha kinase 3 | 13616 | Inparanoid, EggNOG | |
| Platypus | 100081193 | EIF2AK3 | eukaryotic translation initiation factor 2 alpha kinase 3 | 9258 | Inparanoid, OMA, EggNOG | |
| Chicken | 422930 | EIF2AK3 | eukaryotic translation initiation factor 2 alpha kinase 3 | 9031 | CGNC:11912 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100551680 | eif2ak3 | eukaryotic translation initiation factor 2 alpha kinase 3 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100190763 | eif2ak3 | eukaryotic translation initiation factor 2 alpha kinase 3 | 8364 | XB-GENE-989849 | Inparanoid, OMA, EggNOG |
| Zebrafish | 559564 | eif2ak3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 7955 | ZDB-GENE-050414-2 | Inparanoid, OMA, EggNOG |
| C. elegans | 181334 | pek-1 | Eukaryotic translation initiation factor 2-alpha kinase pek-1 | 6239 | Inparanoid, OMA, EggNOG | |
| Fruitfly | 40653 | PEK | pancreatic eIF-2alpha kinase | 7227 | FBgn0037327 | Inparanoid, EggNOG |
Protein Classes
PANTHER Classes
protein / non-receptor serine/threonine protein kinase / Eukaryotic translation initiation factor 2-alpha kinase 3
protein / protein kinase / Eukaryotic translation initiation factor 2-alpha kinase 3
protein / transferase / Eukaryotic translation initiation factor 2-alpha kinase 3
protein / kinase / Eukaryotic translation initiation factor 2-alpha kinase 3
protein / non-receptor serine/threonine protein kinase / Eukaryotic translation initiation factor 2-alpha kinase 3
protein / protein kinase / Eukaryotic translation initiation factor 2-alpha kinase 3
protein / transferase / Eukaryotic translation initiation factor 2-alpha kinase 3
protein / kinase / Eukaryotic translation initiation factor 2-alpha kinase 3
DTO Classes
protein / Kinase / Protein kinase / Other group / PEK family / PEK subfamily / Eukaryotic translation initiation factor 2-alpha kinase 3
protein / Kinase / Protein kinase / Other group / PEK family / PEK subfamily / Eukaryotic translation initiation factor 2-alpha kinase 3
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
|---|
Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
|---|
Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
|---|
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
|---|