KDM1A
| Description | Lysine-specific histone demethylase 1A |
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Gene and Protein Information
| Gene ID | 23028 |
|---|---|
| Uniprot Accession IDs | A8MWP9 Q5TH94 Q5TH95 Q86VT7 Q8IXK4 Q8NDP6 Q8TAZ3 Q96AW4 |
| Ensembl ID | ENSP00000383042 |
| Symbol | AOF2 KDM1 KIAA0601 LSD1 AOF2 CPRF KDM1 LSD1 BHC110 |
| Family | Belongs to the flavin monoamine oxidase family. |
| Sequence | MLSGKKAAAAAAAAAAAATGTEAGPGTAGGSENGSEVAAQPAGLSGPAEVGPGAVGERTPRKKEPPRASPPGGLAEPPGSAGPQAGPTVVPGSATPMETGIAETPEGRRTSRRKRAKVEYREMDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLPRQATPGVPAQQSPSM Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 456614 | KDM1A | lysine demethylase 1A | 9598 | VGNC:8065 | OMA, EggNOG |
| Macaque | 718609 | KDM1A | lysine demethylase 1A | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 99982 | Kdm1a | lysine (K)-specific demethylase 1A | 10090 | MGI:1196256 | Inparanoid, OMA, EggNOG |
| Rat | 500569 | Kdm1a | lysine demethylase 1A | 10116 | RGD:1562975 | Inparanoid, OMA |
| Dog | 478193 | KDM1A | lysine demethylase 1A | 9615 | VGNC:42318 | Inparanoid, OMA, EggNOG |
| Horse | 100071646 | KDM1A | lysine demethylase 1A | 9796 | VGNC:19331 | Inparanoid, OMA, EggNOG |
| Cow | 532997 | KDM1A | lysine demethylase 1A | 9913 | VGNC:30522 | Inparanoid, OMA, EggNOG |
| Pig | 100127157 | KDM1A | lysine demethylase 1A | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100025161 | KDM1A | lysine demethylase 1A | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | KDM1A | lysine demethylase 1A [Source:HGNC Symbol;Acc:HGNC:29079] | 9258 | OMA, EggNOG | ||
| Anole lizard | 100557968 | kdm1a | lysine demethylase 1A | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100216250 | kdm1a | lysine (K)-specific demethylase 1A | 8364 | XB-GENE-5816927 | Inparanoid, OMA, EggNOG |
| Zebrafish | 558450 | kdm1a | lysine (K)-specific demethylase 1a | 7955 | ZDB-GENE-030131-7828 | Inparanoid, OMA, EggNOG |
| Fruitfly | 40217 | Su(var)3-3 | Suppressor of variegation 3-3 | 7227 | FBgn0260397 | Inparanoid, EggNOG |
Protein Classes
PANTHER Classes
protein / nucleic acid binding / oxidase / Lysine-specific histone demethylase 1A
protein / nucleic acid binding / DNA binding protein / Lysine-specific histone demethylase 1A
protein / nucleic acid binding / methyltransferase / Lysine-specific histone demethylase 1A
protein / nucleic acid binding / DNA methyltransferase / Lysine-specific histone demethylase 1A
protein / nucleic acid binding / oxidase / Lysine-specific histone demethylase 1A
protein / nucleic acid binding / DNA binding protein / Lysine-specific histone demethylase 1A
protein / nucleic acid binding / methyltransferase / Lysine-specific histone demethylase 1A
protein / nucleic acid binding / DNA methyltransferase / Lysine-specific histone demethylase 1A
DTO Classes
protein / Epigenetic regulator / Eraser / Lysine demethylase / Lysine-specific demethylase / Lysine-specific histone demethylase 1A
protein / Epigenetic regulator / Eraser / Lysine demethylase / Lysine-specific demethylase / Lysine-specific histone demethylase 1A
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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