KDM6A

DescriptionLysine-specific demethylase 6A

Gene and Protein Information

Gene ID7403
Uniprot Accession IDs Q52LL9 Q5JVQ7
Ensembl ID ENSP00000367203
Symbol UTX UTX KABUK2 bA386N14.2
FamilyBelongs to the UTX family.
Sequence
MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFVRFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp465593KDM6Alysine demethylase 6A9598VGNC:12441OMA, EggNOG
Mouse22289Kdm6alysine (K)-specific demethylase 6A10090MGI:1095419Inparanoid, OMA, EggNOG
Rat103689969Kdm6alysine demethylase 6A10116RGD:9275041Inparanoid, OMA
Dog491845KDM6Alysine demethylase 6A9615VGNC:54168Inparanoid, OMA, EggNOG
Horse100059800KDM6Alysine demethylase 6A9796Inparanoid, OMA, EggNOG
Cow280952KDM6Alysine demethylase 6A9913OMA, EggNOG
Opossum100016846KDM6Alysine demethylase 6A13616OMA, EggNOG
Chicken418556KDM6Alysine demethylase 6A9031CGNC:50790Inparanoid, OMA, EggNOG
Anole lizard100564779kdm6alysine demethylase 6A28377OMA, EggNOG
Xenopus100170558kdm6alysine demethylase 6A8364XB-GENE-960316Inparanoid, OMA, EggNOG
Zebrafish569277kdm6alysine (K)-specific demethylase 6A7955ZDB-GENE-081105-56OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transcription factor    /    Lysine-specific demethylase 6A
DTO Classes
protein    /    Epigenetic regulator    /    Eraser    /    Lysine demethylase    /    Jumonji domain-containing    /    Lysine-specific demethylase 6A

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source