PKLR

DescriptionPyruvate kinase PKLR

Gene and Protein Information

Gene ID5313
Uniprot Accession IDs O75758 P11973
Ensembl ID ENSP00000339933
Symbol PK1 PKL PK1 PKL RPK PKRL
FamilyBelongs to the pyruvate kinase family.
Sequence
MSIQENISSLQLRSWVSKSQRDLAKSILIGAPGGPAGYLRRASVAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp469513PKLRpyruvate kinase L/R9598VGNC:48991OMA, EggNOG
Macaque719152PKLRpyruvate kinase L/R9544Inparanoid, OMA, EggNOG
Mouse18770Pklrpyruvate kinase liver and red blood cell10090MGI:97604Inparanoid, OMA, EggNOG
Rat24651Pklrpyruvate kinase L/R10116RGD:3336Inparanoid, OMA, EggNOG
Dog490425PKLRpyruvate kinase L/R9615VGNC:44609Inparanoid, OMA, EggNOG
Horse100063608PKLRpyruvate kinase L/R9796VGNC:21496Inparanoid, OMA, EggNOG
Cow539579PKLRpyruvate kinase L/R9913VGNC:32943Inparanoid, OMA, EggNOG
Pig100738344PKLRpyruvate kinase L/R9823OMA, EggNOG
Opossum100022269PKLRpyruvate kinase L/R13616Inparanoid, OMA, EggNOG
Xenopus100380137pklrpyruvate kinase L/R8364XB-GENE-5918041OMA, EggNOG
C. elegans172744pyk-1Pyruvate kinase6239Inparanoid, OMA
C. elegans177984pyk-2Pyruvate kinase6239OMA, EggNOG
Fruitfly42620PyKPyruvate kinase7227FBgn0267385Inparanoid, EggNOG
S.cerevisiae854529PYK2pyruvate kinase PYK24932S000005874Inparanoid, OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Non-protein kinase    /    Other small molecule kinase    /    Pyruvate kinase PKLR

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source