PRKG2

DescriptioncGMP-dependent protein kinase 2

Gene and Protein Information

Gene ID5593
Uniprot Accession IDs B4DMX3 E7EPE6 O00125 O60916 cGK 2
Ensembl ID ENSP00000264399
Symbol PRKGR2 PKG2 cGK2 cGKII PRKGR2
FamilyBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.
Sequence
MGNGSVKPKHSKHPDGHSGNLTTDALRNKVTELERELRRKDAEIQEREYHLKELREQLSKQTVAIAELTEELQNKCIQLNKLQDVVHMQGGSPLQASPDKVPLEVHRKTSGLVSLHSRRGAKAGVSAEPTTRTYDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVFQGEKLLSSIPMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVGTFEELQKYLEGYVANLNRDDEKRHAKRSMSNWKLSKALSLEMIQLKEKVARFSSSSPFQNLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYPPEKGMPPDELSGWDKDF
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp461217PRKG2protein kinase, cGMP-dependent, type II9598OMA, EggNOG
Macaque696308PRKG2protein kinase, cGMP-dependent, type II9544OMA, EggNOG
Mouse19092Prkg2protein kinase, cGMP-dependent, type II10090MGI:108173Inparanoid, OMA, EggNOG
Rat25523Prkg2protein kinase cGMP-dependent 210116RGD:3401Inparanoid, OMA, EggNOG
Dog100855930PRKG2protein kinase cGMP-dependent 29615VGNC:44990Inparanoid, OMA, EggNOG
Horse100060358PRKG2protein kinase cGMP-dependent 29796VGNC:21854Inparanoid, OMA, EggNOG
Cow533330PRKG2protein kinase cGMP-dependent 29913VGNC:33341Inparanoid, OMA, EggNOG
Pig100512796PRKG2protein kinase, cGMP-dependent, type II9823Inparanoid, OMA, EggNOG
Opossum100014568PRKG2protein kinase, cGMP-dependent, type II13616Inparanoid, OMA, EggNOG
Chicken428753PRKG2protein kinase, cGMP-dependent, type II9031CGNC:8290Inparanoid, OMA, EggNOG
Anole lizard100561246prkg2protein kinase, cGMP-dependent, type II28377Inparanoid, OMA, EggNOG
Xenopus100497736prkg2protein kinase, cGMP-dependent, type II8364XB-GENE-951552Inparanoid, OMA
Zebrafish100125912prkg2protein kinase cGMP-dependent 27955ZDB-GENE-060531-80Inparanoid, OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    AGC group    /    PKG family    /    Cgmp-dependent protein kinase 2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source