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PRKCD

DescriptionProtein kinase C delta type

Gene and Protein Information

Gene ID5580
Uniprot Accession IDs Q05655 B0KZ81 B2R834 Q15144 Q86XJ6
Ensembl ID ENSP00000378217
Symbol MAY1 PKCD ALPS3 CVID9 nPKC-delta
FamilyBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Sequence
MAPFLRIAFNSYELGSLQAEDEANQPFCAVKMKEALSTERGKTLVQKKPTMYPEWKSTFDAHIYEGRVIQIVLMRAAEEPVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMSVQYFLEDVDCKQSMRSEDEAKFPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKDFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTAANSRDTIFQKERFNIDMPHRFKVHNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQRASRRSDSASSEPVGIYQGFEKKTGVAGEDMQDNSGTYGKIWEGSSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFEREPTKRLGVTGNIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKARLSYSDKNLIDSMDQSAFAGFSFVNPKFEHLLED
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp460442PRKCDprotein kinase C delta9598VGNC:7105OMA, EggNOG
Macaque694656PRKCDprotein kinase C delta9544Inparanoid, OMA, EggNOG
Mouse18753Prkcdprotein kinase C, delta10090MGI:97598Inparanoid, OMA
Rat170538Prkcdprotein kinase C, delta10116RGD:67383Inparanoid, OMA
Dog494005PRKCDprotein kinase C delta9615VGNC:44979Inparanoid, OMA
Horse100051333PRKCDprotein kinase C delta9796VGNC:21844Inparanoid, OMA
Cow505708PRKCDprotein kinase C delta9913VGNC:33329Inparanoid, OMA
Opossum100030722PRKCDprotein kinase C delta13616Inparanoid, OMA
Chicken415905PRKCDprotein kinase C delta9031CGNC:50113Inparanoid, OMA
Anole lizard100553700prkcdprotein kinase C delta28377Inparanoid, OMA
Xenopus733756prkcdprotein kinase C delta8364XB-GENE-478663Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    calcium-binding protein    /    non-receptor serine/threonine protein kinase    /    Protein kinase c delta type
protein    /    calcium-binding protein    /    transfer/carrier protein    /    Protein kinase c delta type
protein    /    calcium-binding protein    /    protein kinase    /    Protein kinase c delta type
protein    /    calcium-binding protein    /    calmodulin    /    Protein kinase c delta type
protein    /    calcium-binding protein    /    annexin    /    Protein kinase c delta type
protein    /    calcium-binding protein    /    transferase    /    Protein kinase c delta type
protein    /    calcium-binding protein    /    kinase    /    Protein kinase c delta type
DTO Classes
protein    /    Kinase    /    Protein kinase    /    AGC group    /    PKC family    /    PKC delta subfamily    /    Protein kinase c delta type

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

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NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      1.Schneider, A A, Biernat, J J, von Bergen, M M, Mandelkow, E E and Mandelkow, E M EM. 1999-03-23 Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments. [PMID:10090741]
      2.Zhu, G G, Qu, Z Z, Cui, N N and Jiang, C C. 1999-04-23 Suppression of Kir2.3 activity by protein kinase C phosphorylation of the channel protein at threonine 53. [PMID:10206975]
      3.Fleming, I N IN, Elliott, C M CM, Buchanan, F G FG, Downes, C P CP and Exton, J H JH. 1999-04-30 Ca2+/calmodulin-dependent protein kinase II regulates Tiam1 by reversible protein phosphorylation. [PMID:10212259]
      4.Schullery, D S DS and 7 more authors. 1999-05-21 Regulated interaction of protein kinase Cdelta with the heterogeneous nuclear ribonucleoprotein K protein. [PMID:10329716]
      5.Ron, D D and 10 more authors. 1999-07-02 Direct interaction in T-cells between thetaPKC and the tyrosine kinase p59fyn. [PMID:10383400]
      6.Autieri, M V MV and Carbone, C J CJ. 1999-07 14-3-3Gamma interacts with and is phosphorylated by multiple protein kinase C isoforms in PDGF-stimulated human vascular smooth muscle cells. [PMID:10433554]
      7.Jain, N N, Zhang, T T, Kee, W H WH, Li, W W and Cao, X X. 1999-08-20 Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner. [PMID:10446219]
      8.Lim, C P CP and Cao, X X. 1999-10-22 Serine phosphorylation and negative regulation of Stat3 by JNK. [PMID:10521505]
      9.Tseng, C P CP and 5 more authors. 1999-11-05 The role of DOC-2/DAB2 protein phosphorylation in the inhibition of AP-1 activity. An underlying mechanism of its tumor-suppressive function in prostate cancer. [PMID:10542228]
      10.Lu, J J, O'Hara, E B EB, Trieselmann, B A BA, Romano, P R PR and Dever, T E TE. 1999-11-05 The interferon-induced double-stranded RNA-activated protein kinase PKR will phosphorylate serine, threonine, or tyrosine at residue 51 in eukaryotic initiation factor 2alpha. [PMID:10542257]