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Protein or Target Summary

Tyrosine-protein kinase SYK

Gene ID6850
uniprotP43405
Gene NameSYK
Ensernbl IDENSP00000364907
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.
Sequence
MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPFEDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPKPGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN6850SYKTyrosine-protein kinase SYKP43405
MOUSEsykProtein tyrosine kinaseQ6LEP4
MOUSESykUncharacterized proteinQ3V3Q2
MOUSE20963SykTyrosine-protein kinaseQ6P1E0
MOUSESykTyrosine-protein kinaseE9PWE9
MOUSE20963SykTyrosine-protein kinaseQ3UPF7
MOUSE20963SykTyrosine-protein kinase SYKP48025
RATSykTyrosine-protein kinaseD3ZH44
RATSykTyrosine-protein kinaseG3V7N4
RAT25155SykTyrosine-protein kinase SYKQ64725

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    SYK family    /    Tyrosine-protein kinase syk

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
      Source: DataSourcesLicenses.xlsx
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