SYK

DescriptionTyrosine-protein kinase SYK

Gene and Protein Information

Gene ID6850
Uniprot Accession IDs P43405
Ensembl ID ENSP00000364907
Symbol p72-Syk
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.
Sequence
MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPFEDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPKPGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp464586SYKspleen associated tyrosine kinase9598VGNC:13975OMA, EggNOG
Macaque704102SYKspleen associated tyrosine kinase9544Inparanoid, OMA, EggNOG
Mouse20963Sykspleen tyrosine kinase10090MGI:99515Inparanoid, OMA, EggNOG
Rat25155Sykspleen associated tyrosine kinase10116RGD:3796Inparanoid, OMA, EggNOG
Dog484196SYKspleen associated tyrosine kinase9615VGNC:47021Inparanoid, OMA, EggNOG
Horse100063383SYKspleen associated tyrosine kinase9796VGNC:23794Inparanoid, OMA, EggNOG
Cow515515SYKspleen associated tyrosine kinase9913VGNC:35513Inparanoid, OMA, EggNOG
OpossumSYKspleen associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11491]13616Inparanoid, OMA, EggNOG
Chicken427272SYKspleen associated tyrosine kinase9031CGNC:53036Inparanoid, OMA
Anole lizard100554859sykspleen associated tyrosine kinase28377Inparanoid, OMA, EggNOG
Xenopus100486846sykspleen tyrosine kinase8364XB-GENE-978184Inparanoid, OMA
Zebrafish405769sykspleen tyrosine kinase7955ZDB-GENE-040702-3Inparanoid, OMA, EggNOG
Fruitfly44353SharkSH2 ankyrin repeat kinase7227FBgn0015295Inparanoid, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    SYK family    /    Tyrosine-protein kinase syk

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source