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Protein or Target Summary

Dihydrofolate reductase

Gene ID1719
uniprotP00374
Gene NameDHFR
Ensernbl IDENSP00000396308
FamilyBelongs to the dihydrofolate reductase family.
Sequence
MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN1719DHFRDihydrofolate reductaseP00374
MOUSE13361DhfrDihydrofolate reductaseP00375
MOUSE13361DhfrDihydrofolate reductaseQ544T5
RAT24312DhfrDihydrofolate reductaseQ920D2
RAT24312DhfrDihydrofolate reductaseB0BMV8

Protein Classes

PANTHER Classes
protein    /    oxidoreductase    /    reductase    /    Dihydrofolate reductase
DTO Classes
protein    /    Enzyme    /    Oxidoreductase    /    Reductase    /    Dihydrofolate reductase

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source