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Protein or Target Summary

Mitogen-activated protein kinase 8

Gene ID5599
uniprotP45983
Gene NameMAPK8
Ensernbl IDENSP00000378974
FamilyBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Sequence
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAAGPLGCCR
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN5599MAPK8Mitogen-activated protein kinase 8P45983
MOUSEMapk8Mitogen-activated protein kinaseA3KBF5
MOUSEMapk8Mitogen-activated protein kinaseD3Z1Z4
MOUSEMapk8Mitogen-activated protein kinase 8A0A2I3BPL3
MOUSE26419Mapk8Mitogen-activated protein kinaseA6P3E4
MOUSE26419Mapk8Mitogen-activated protein kinaseG3X8U9
MOUSE26419Mapk8Mitogen-activated protein kinaseQ7TSJ7
MOUSE26419Mapk8Mitogen-activated protein kinaseQ544A0
MOUSE26419Mapk8Mitogen-activated protein kinase 8Q91Y86
RATMapk8Mitogen-activated protein kinaseA0A0G2KA63
RATMapk8Mitogen-activated protein kinaseF1LP66
RAT116554Mapk8Mitogen-activated protein kinase 8P49185

Protein Classes

PANTHER Classes
protein    /    non-receptor serine/threonine protein kinase    /    Mitogen-activated protein kinase 8
protein    /    protein kinase    /    Mitogen-activated protein kinase 8
protein    /    transferase    /    Mitogen-activated protein kinase 8
protein    /    kinase    /    Mitogen-activated protein kinase 8
DTO Classes
protein    /    Kinase    /    Protein kinase    /    CMGC group    /    MAPK family    /    JNK subfamily    /    Mitogen-activated protein kinase 8

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source