MAPK8

DescriptionMitogen-activated protein kinase 8

Gene and Protein Information

Gene ID5599
Uniprot Accession IDs B5BTZ5 B7ZLV4 D3DX88 D3DX92 Q15709 Q15712 Q15713 Q308M2 MAP kinase 8
Ensembl ID ENSP00000378974
Symbol JNK1 PRKM8 SAPK1 SAPK1C JNK JNK1 PRKM8 SAPK1 JNK-46 JNK1A2 SAPK1c JNK21B1/2
FamilyBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Sequence
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAAGPLGCCR
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp450445MAPK8mitogen-activated protein kinase 89598VGNC:14517OMA, EggNOG
Macaque711115MAPK8mitogen-activated protein kinase 89544Inparanoid, OMA, EggNOG
Rat116554Mapk8mitogen-activated protein kinase 810116RGD:621506Inparanoid, OMA
Dog477746MAPK8mitogen-activated protein kinase 89615VGNC:43001Inparanoid, OMA
Horse100051798MAPK8mitogen-activated protein kinase 89796VGNC:19962Inparanoid, OMA
Cow539941MAPK8mitogen-activated protein kinase 89913VGNC:31223OMA, EggNOG
Pig396610MAPK8mitogen-activated protein kinase 89823OMA, EggNOG
Chicken423778MAPK8mitogen-activated protein kinase 89031CGNC:4584Inparanoid, OMA
Anole lizard100561907mapk8mitogen-activated protein kinase 828377Inparanoid, OMA
Zebrafish562720mapk8amitogen-activated protein kinase 8a7955ZDB-GENE-080218-17Inparanoid, OMA
C. elegans177460jnk-1Stress-activated protein kinase jnk-16239OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    non-receptor serine/threonine protein kinase    /    Mitogen-activated protein kinase 8
protein    /    protein kinase    /    Mitogen-activated protein kinase 8
protein    /    transferase    /    Mitogen-activated protein kinase 8
protein    /    kinase    /    Mitogen-activated protein kinase 8
DTO Classes
protein    /    Kinase    /    Protein kinase    /    CMGC group    /    MAPK family    /    JNK subfamily    /    Mitogen-activated protein kinase 8

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source