SLC1A1

DescriptionExcitatory amino acid transporter 3

Gene and Protein Information

Gene ID6505
Uniprot Accession IDs O75587 Q5VZ24 Q8N199 Q9UEW2
Ensembl ID ENSP00000262352
Symbol EAAC1 EAAT3 DCBXA EAAC1 EAAT3 SCZD18
FamilyBelongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A1 subfamily.
Sequence
MGKPARKGCEWKRFLKNNWVLLSTVAAVVLGITTGVLVREHSNLSTLEKFYFAFPGEILMRMLKLIILPLIISSMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTKREEVKPPSDPEMNMTEESFTAVMTTAISKNKTKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFRKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMDVSSEVNIVNPFALESTILDNEDSDTKKSYVNGGFAVDKSDTISFTQTSQF
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp464974SLC1A1solute carrier family 1 member 19598VGNC:8928OMA, EggNOG
Macaque694947SLC1A1solute carrier family 1 member 19544Inparanoid, OMA, EggNOG
Mouse20510Slc1a1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 110090MGI:105083Inparanoid, OMA, EggNOG
Rat25550Slc1a1solute carrier family 1 member 110116RGD:3696Inparanoid, OMA, EggNOG
Dog403751SLC1A1solute carrier family 1 member 19615VGNC:46261Inparanoid, OMA, EggNOG
Horse100059120SLC1A1solute carrier family 1 member 19796VGNC:23060Inparanoid, OMA, EggNOG
Cow282353SLC1A1solute carrier family 1 member 19913VGNC:34711Inparanoid, OMA, EggNOG
Pig397003SLC1A1solute carrier family 1 member 19823Inparanoid, OMA, EggNOG
Opossum100014691SLC1A1solute carrier family 1 member 113616Inparanoid, OMA, EggNOG
Platypus100073939SLC1A1solute carrier family 1 member 19258Inparanoid, OMA, EggNOG
Chicken427352SLC1A1solute carrier family 1 member 19031CGNC:7747OMA, EggNOG
Anole lizard100566728slc1a1solute carrier family 1 member 128377Inparanoid, OMA, EggNOG
Xenopusslc1a1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 [Source:Xenbase;Acc:XB-GENE-1011544]8364OMA, EggNOG
Zebrafish436939slc1a1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 17955ZDB-GENE-040718-414Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transporter    /    cation transporter    /    Excitatory amino acid transporter 3
DTO Classes
protein    /    Transporter    /    SLC superfamily of solute carriers    /    SLC1 family of amino acid transporters    /    Glutamate transporter subfamily    /    Excitatory amino acid transporter 3

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source