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SLC16A10

DescriptionMonocarboxylate transporter 10

Gene and Protein Information

Gene ID117247
Uniprot Accession IDs B3KWY0 Q6ZMG0 Q8WVI5 MCT 10
Ensembl ID ENSP00000357844
Symbol MCT10 TAT1 TAT1 MCT10 PRO0813
FamilyBelongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
Sequence
MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIFMFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIPWIHSKKQREISKTTGKEKMEKMLENQNSLLSSSSGMFKKESDSII
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp462941SLC16A10solute carrier family 16 member 109598VGNC:7910OMA, EggNOG
Mouse72472Slc16a10solute carrier family 16 (monocarboxylic acid transporters), member 1010090MGI:1919722Inparanoid, OMA
Rat170566Slc16a10solute carrier family 16 member 1010116RGD:69197Inparanoid, OMA
Dog612335SLC16A10solute carrier family 16 member 109615VGNC:46236Inparanoid, OMA, EggNOG
Horse100072381SLC16A10solute carrier family 16 member 109796VGNC:23036Inparanoid, OMA, EggNOG
Cow541240SLC16A10solute carrier family 16 member 109913VGNC:34684Inparanoid, OMA
OpossumSLC16A10solute carrier family 16 member 10 [Source:HGNC Symbol;Acc:HGNC:17027]13616Inparanoid, OMA
Chicken421753SLC16A10solute carrier family 16 member 109031CGNC:11185Inparanoid, OMA, EggNOG
Anole lizard100559511slc16a10solute carrier family 16 member 1028377Inparanoid, OMA, EggNOG
Xenopus100488837slc16a10solute carrier family 16 member 108364XB-GENE-1012623Inparanoid, OMA
Zebrafish566499slc16a10solute carrier family 16 (aromatic amino acid transporter), member 107955ZDB-GENE-040724-214Inparanoid, OMA
S.cerevisiae854030MCH4Mch4p4932S000005479Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    Monocarboxylate transporter 10
DTO Classes
protein    /    Transporter    /    SLC superfamily of solute carriers    /    SLC16 family of monocarboxylate transporters    /    Monocarboxylate transporter 10

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      Bibliography

      1.Kim, D K DK and 5 more authors. 2001-05-18 Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. [PMID:11278508]
      2.Toure, A A and 5 more authors. 2001-06-08 Tat1, a novel sulfate transporter specifically expressed in human male germ cells and potentially linked to rhogtpase signaling. [PMID:11278976]
      3.Kim, Do Kyung DK and 9 more authors. 2002-01 The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location. [PMID:11827462]
      4.Strausberg, Robert L RL and 83 more authors. 2002-12-24 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. [PMID:12477932]
      5.Halestrap, Andrew P AP and Meredith, David D. 2004-02 The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. [PMID:12739169]
      6.Park, Sun Young SY and 10 more authors. 2005-04 Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule. [PMID:15918515]
      7. and Bröer, Stefan S. 2008-01 Amino acid transport across mammalian intestinal and renal epithelia. [PMID:18195088]
      8.Friesema, Edith C H EC and 5 more authors. 2008-06 Effective cellular uptake and efflux of thyroid hormone by human monocarboxylate transporter 10. [PMID:18337592]
      9.Loubière, L S LS and 9 more authors. 2010-04 Expression of thyroid hormone transporters in the human placenta and changes associated with intrauterine growth restriction. [PMID:20167367]
      10.Visser, W Edward WE, van Mullem, Alies A A AA, Jansen, Jurgen J and Visser, Theo J TJ. 2011-04-30 The thyroid hormone transporters MCT8 and MCT10 transport the affinity-label N-bromoacetyl-[(125)I]T3 but are not modified by it. [PMID:21315799]