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MAP4K2

Description	Mitogen-activated protein kinase kinase kinase kinase 2

Gene and Protein Information

Gene ID	5871
Uniprot Accession IDs	Q86VU3
Ensembl ID	ENSP00000294066
Symbol	GCK RAB8IP GCK BL44 RAB8IP
Family	Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Sequence	MALLRDVSLQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQQEITILRECRHPNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREALKGLHHLHSQGKIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPEVAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQNFHHFLKLALTKNPKKRPTAEKLLQHPFTTQQLPRALLTQLLDKASDPHLGTPSPEDCELETYDMFPDTIHSRGQHGPAERTPSEIQFHQVKFGAPRRKETDPLNEPWEEEWTLLGKEELSGSLLQSVQEALEERSLTIRSASEFQELDSPDDTMGTIKRAPFLGPLPTDPPAEEPLSSPPGTLPPPPSGPNSSPLLPTAWATMKQREDPERSSCHGLPPTPKVHMGACFSKVFNGCPLRIHAAVTWIHPVTRDQFLVVGAEEGIYTLNLHELHEDTLEKLISHRCSWLYCVNNVLLSLSGKSTHIWAHDLPGLFEQRRLQQQVPLSIPTNRLTQRIIPRRFALSTKIPDTKGCLQCRVVRNPYTGATFLLAALPTSLLLLQWYEPLQKFLLLKNFSSPLPSPAGMLEPLVLDGKELPQVCVGAEGPEGPGCRVLFHVLPLEAGLTPDILIPPEGIPGSAQQVIQVDRDTILVSFERCVRIVNMQGEPTATLAPELTFDFPIETVVCLQDSVLAFWSHGMQGRSLDTNEVTQEITDETRIFRVLGAHRDIILESIPTDNPEAHSNLYILTGHQSTY Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	451301	MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2	9598	VGNC:7507	OMA, EggNOG
Macaque	699331	MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2	9544		OMA, EggNOG
Mouse	26412	Map4k2	mitogen-activated protein kinase kinase kinase kinase 2	10090	MGI:1346883	Inparanoid, OMA, EggNOG
Rat	293694	Map4k2	mitogen activated protein kinase kinase kinase kinase 2	10116	RGD:1308199	Inparanoid, OMA
Dog	483759	MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2	9615	VGNC:42982	Inparanoid, OMA
Horse	100056001	MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2	9796	VGNC:19946	Inparanoid, OMA
Cow	520058	MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2	9913	VGNC:31205	Inparanoid, OMA
Pig	100523716	MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2	9823		Inparanoid, OMA
C. elegans	179072	gck-2	Mitogen-activated protein kinase kinase kinase kinase	6239		Inparanoid, OMA

Protein Classes

DTO Classes
protein / Kinase / Protein kinase / STE group / STE20 family / KHS subfamily / Mitogen-activated protein kinase kinase kinase kinase 2

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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