MGMT

DescriptionMethylated-DNA--protein-cysteine methyltransferase

Gene and Protein Information

Gene ID4255
Uniprot Accession IDs Q5VY78
Ensembl ID ENSP00000302111
FamilyBelongs to the MGMT family.
Sequence
MDKDCEMKRTTLDSPLGKLELSGCEQGLHEIKLLGKGTSAADAVEVPAPAAVLGGPEPLMQCTAWLNAYFHQPEAIEEFPVPALHHPVFQQESFTRQVLWKLLKVVKFGEVISYQQLAALAGNPKAARAVGGAMRGNPVPILIPCHRVVCSSGAVGNYSGGLAVKEWLLAHEGHRLGKPGLGGSSGLAGAWLKGAGATSGSPPAGRN
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp737624MGMTO-6-methylguanine-DNA methyltransferase9598VGNC:7280OMA, EggNOG
Macaque698134MGMTO-6-methylguanine-DNA methyltransferase9544Inparanoid, OMA, EggNOG
Mouse17314MgmtO-6-methylguanine-DNA methyltransferase10090MGI:96977Inparanoid, OMA, EggNOG
Rat25332MgmtO-6-methylguanine-DNA methyltransferase10116RGD:3087Inparanoid, OMA, EggNOG
Dog442978MGMTO-6-methylguanine-DNA methyltransferase9615VGNC:43213Inparanoid, OMA, EggNOG
Horse100049801MGMTO-6-methylguanine-DNA methyltransferase9796VGNC:20163Inparanoid, OMA, EggNOG
Pig100155050MGMTO-6-methylguanine-DNA methyltransferase9823Inparanoid, OMA, EggNOG
Anole lizard100553369mgmtO-6-methylguanine-DNA methyltransferase28377Inparanoid, EggNOG
Xenopus496878mgmtO-6-methylguanine-DNA methyltransferase8364XB-GENE-941688Inparanoid, OMA, EggNOG
Zebrafish553368mgmtO-6-methylguanine-DNA methyltransferase7955ZDB-GENE-120614-1Inparanoid, OMA, EggNOG

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source