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Protein or Target Summary

Mixed lineage kinase domain-like protein

Gene ID	197259
uniprot	Q8NB16
Gene Name	MLKL
Ensernbl ID	ENSP00000308351
Family	Belongs to the protein kinase superfamily.
Sequence	MENLKHIITLGQVIHKRCEEMKYCKKQCRRLGHRVLGLIKPLEMLQDQGKRSVPSEKLTTAMNRFKAALEEANGEIEKFSNRSNICRFLTASQDKILFKDVNRKLSDVWKELSLLLQVEQRMPVSPISQGASWAQEDQQDADEDRRAFQMLRRDNEKIEASLRRLEINMKEIKETLRQYLPPKCMQEIPQEQIKEIKKEQLSGSPWILLRENEVSTLYKGEYHRAPVAIKVFKKLQAGSIAIVRQTFNKEIKTMKKFESPNILRIFGICIDETVTPPQFSIVMEYCELGTLRELLDREKDLTLGKRMVLVLGAARGLYRLHHSEAPELHGKIRSSNFLVTQGYQVKLAGFELRKTQTSMSLGTTREKTDRVKSTAYLSPQELEDVFYQYDVKSEIYSFGIVLWEIATGDIPFQGCNSEKIRKLVAVKRQQEPLGEDCPSELREIIDECRAHDPSVRPSVDEILKKLSTFSK Show more

Gene and Protein Information

Species	Gene ID	Gene Symbol	Gene Name	Uniprot
HUMAN	197259	MLKL	Mixed lineage kinase domain-like protein	Q8NB16
MOUSE		Mlkl	Mixed lineage kinase domain-like protein	D3YV42
MOUSE	74568	Mlkl	Mixed lineage kinase domain-like protein	Q9D2Y4
RAT	690743	Mlkl	Mixed lineage kinase domain-like pseudokinase	D3ZKP6

Protein Classes

DTO Classes
protein / Kinase / Protein kinase / TKL group / TKL-UNIQUE family / Mixed lineage kinase domain-like protein

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

Source: DataSourcesLicenses.xlsx