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LRP6
| Description | Low-density lipoprotein receptor-related protein 6 |
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Gene and Protein Information
| Gene ID | 4040 |
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| Uniprot Accession IDs | Q17RZ2 LRP-6 |
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| Ensembl ID | ENSP00000261349 |
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| Symbol | ADCAD2 STHAG7 |
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| Family | Belongs to the LDLR family. |
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| Sequence | MGAVLRSLLACSFCVLLRAAPLLLYANRRDLRLVDATNGKENATIVVGGLEDAAAVDFVFSHGLIYWSDVSEEAIKRTEFNKTESVQNVVVSGLLSPDGLACDWLGEKLYWTDSETNRIEVSNLDGSLRKVLFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGSSRFIIINSEIYWPNGLTLDYEEQKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDILYWTDWSTHSILACNKYTGEGLREIHSDIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCLMSPVKPFYQCACPTGVKLLENGKTCKDGATELLLLARRTDLRRISLDTPDFTDIVLQLEDIRHAIAIDYDPVEGYIYWTDDEVRAIRRSFIDGSGSQFVVTAQIAHPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMVGYMYWTDWGEIPKIERAALDGSDRVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTLLGDYVYWTDWQRRSIERVHKRSAEREVIIDQLPDLMGLKATNVHRVIGSNPCAEENGGCSHLCLYRPQGLRCACPIGFELISDMKTCIVPEAFLLFSRRADIRRISLETNNNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLYWADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGKPKIDRAAMDGSERTTLVPNVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNREVIADDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQNRTIIQGHLDYVMDILVFHSSRQSGWNECASSNGHCSHLCLAVPVGGFVCGCPAHYSLNADNRTCSAPTTFLLFSQKSAINRMVIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSSVPSQNLEIQPYDLSIDIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQDRPRAVVVNPEKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVKGDGTTRCSCPMHLVLLQDELSCGEPPTCSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDELNCPVCSESQFQCASGQCIDGALRCNGDANCQDKSDEKNCEVLCLIDQFRCANGQCIGKHKKCDHNVDCSDKSDELDCYPTEEPAPQATNTVGSVIGVIVTIFVSGTVYFICQRMLCPRMKGDGETMTNDYVVHGPASVPLGYVPHPSSLSGSLPGMSRGKSMISSLSIMGGSSGPPYDRAHVTGASSSSSSSTKGTYFPAILNPPPSPATERSHYTMEFGYSSNSPSTHRSYSYRPYSYRHFAPPTTPCSTDVCDSDYAPSRRMTSVATAKGYTSDLNYDSEPVPPPPTPRSQYLSAEENYESCPPSPYTERSYSHHLYPPPPSPCTDSS Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 465295 | LRP6 | LDL receptor related protein 6 | 9598 | VGNC:13205 | OMA, EggNOG |
| Mouse | 16974 | Lrp6 | low density lipoprotein receptor-related protein 6 | 10090 | MGI:1298218 | Inparanoid, OMA, EggNOG |
| Rat | 312781 | Lrp6 | LDL receptor related protein 6 | 10116 | RGD:1304749 | Inparanoid, OMA |
| Dog | 477692 | LRP6 | LDL receptor related protein 6 | 9615 | VGNC:42778 | Inparanoid, OMA, EggNOG |
| Horse | 100063409 | LRP6 | LDL receptor related protein 6 | 9796 | VGNC:19764 | Inparanoid, OMA, EggNOG |
| Cow | 536328 | LRP6 | LDL receptor related protein 6 | 9913 | VGNC:30993 | Inparanoid, OMA |
| Pig | 100515777 | LRP6 | LDL receptor related protein 6 | 9823 | | Inparanoid, OMA |
| Opossum | 100018443 | LRP6 | LDL receptor related protein 6 | 13616 | | Inparanoid, OMA, EggNOG |
| Platypus | 100077194 | LRP6 | LDL receptor related protein 6 | 9258 | | Inparanoid, OMA |
| Anole lizard | 100554684 | lrp6 | LDL receptor related protein 6 | 28377 | | Inparanoid, OMA |
| Xenopus | 100489328 | lrp6 | LDL receptor related protein 6 | 8364 | XB-GENE-481820 | Inparanoid, OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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