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GAA
| Description | Lysosomal alpha-glucosidase |
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Gene and Protein Information
| Gene ID | 2548 |
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| Uniprot Accession IDs | Q09GN4 Q14351 Q16302 Q8IWE7 |
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| Ensembl ID | ENSP00000305692 |
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| Symbol | LYAG |
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| Family | Belongs to the glycosyl hydrolase 31 family. |
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| Sequence | MGVRHPPCSHRLLAVCALVSLATAALLGHILLHDFLLVPRELSGSSPVLEETHPAHQQGASRPGPRDAQAHPGRPRAVPTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKLENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPHVHSRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQLQKVTVLGVATAPQQVLSNGVPVSNFTYSPDTKVLDICVSLLMGEQFLVSWC Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 454940 | GAA | glucosidase alpha, acid | 9598 | VGNC:9298 | OMA, EggNOG |
| Macaque | 712054 | GAA | glucosidase alpha, acid | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 14387 | Gaa | glucosidase, alpha, acid | 10090 | MGI:95609 | Inparanoid, OMA, EggNOG |
| Rat | 367562 | Gaa | glucosidase, alpha, acid | 10116 | RGD:735227 | Inparanoid, OMA, EggNOG |
| Dog | 483352 | GAA | glucosidase alpha, acid | 9615 | VGNC:41044 | Inparanoid, OMA, EggNOG |
| Horse | 100056675 | GAA | glucosidase alpha, acid | 9796 | VGNC:18184 | Inparanoid, OMA, EggNOG |
| Cow | 280798 | GAA | glucosidase alpha, acid | 9913 | VGNC:29182 | Inparanoid, OMA, EggNOG |
| Pig | 100526132 | GAA | glucosidase alpha, acid | 9823 | | OMA, EggNOG |
| Opossum | 100030818 | GAA | glucosidase alpha, acid | 13616 | | Inparanoid, OMA, EggNOG |
| Platypus | | GAA | glucosidase alpha, acid [Source:HGNC Symbol;Acc:HGNC:4065] | 9258 | | OMA, EggNOG |
| Anole lizard | 100561813 | gaa | glucosidase alpha, acid | 28377 | | Inparanoid, OMA |
| Xenopus | | gaa | glucosidase, alpha; acid [Source:Xenbase;Acc:XB-GENE-6054131] | 8364 | | OMA, EggNOG |
| Zebrafish | 100002366 | gaa | glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II) | 7955 | ZDB-GENE-070212-2 | Inparanoid, OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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