MAP3K7

DescriptionMitogen-activated protein kinase kinase kinase 7

Gene and Protein Information

Gene ID6885
Uniprot Accession IDs B2RE27 E1P523 O43317 O43319 Q5TDN2 Q5TDN3 Q5TDT7 Q9NTR3 Q9NZ70
Ensembl ID ENSP00000358335
Symbol TAK1 CSCF FMD2 TAK1 MEKK7 TGF1a
FamilyBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Sequence
MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTAYSKPKRGHRKTASFGNILDVPEIVISGNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHPWTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp462888MAP3K7mitogen-activated protein kinase kinase kinase 79598VGNC:7196OMA, EggNOG
Macaque703101MAP3K7mitogen-activated protein kinase kinase kinase 79544Inparanoid, OMA, EggNOG
Mouse26409Map3k7mitogen-activated protein kinase kinase kinase 710090MGI:1346877Inparanoid, OMA, EggNOG
Rat313121Map3k7mitogen activated protein kinase kinase kinase 710116RGD:1309438Inparanoid, EggNOG
Dog102156745MAP3K7mitogen-activated protein kinase kinase kinase 79615VGNC:42977Inparanoid, OMA, EggNOG
Horse100065841MAP3K7mitogen-activated protein kinase kinase kinase 79796VGNC:19941Inparanoid, OMA, EggNOG
Cow529146MAP3K7mitogen-activated protein kinase kinase kinase 79913VGNC:31200Inparanoid, OMA, EggNOG
Opossum100019975MAP3K7mitogen-activated protein kinase kinase kinase 713616Inparanoid, OMA, EggNOG
Platypus100076229MAP3K7mitogen-activated protein kinase kinase kinase 79258OMA, EggNOG
Chicken421808MAP3K7mitogen-activated protein kinase kinase kinase 79031CGNC:11625Inparanoid, OMA, EggNOG
Anole lizard100554725map3k7mitogen-activated protein kinase kinase kinase 728377Inparanoid, OMA, EggNOG
Xenopus100101764map3k7mitogen-activated protein kinase kinase kinase 78364XB-GENE-481530Inparanoid, OMA, EggNOG
Zebrafish553788map3k7mitogen-activated protein kinase kinase kinase 77955ZDB-GENE-041001-135Inparanoid, OMA
Fruitfly39659Tak1TGF-beta activated kinase 17227FBgn0026323Inparanoid, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    MLK family    /    TAK1 subfamily    /    Mitogen-activated protein kinase kinase kinase 7

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source