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MAP4K1
| Description | Mitogen-activated protein kinase kinase kinase kinase 1 |
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Gene and Protein Information
| Gene ID | 11184 |
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| Uniprot Accession IDs | Q92918 |
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| Ensembl ID | ENSP00000465039 |
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| Symbol | HPK1 HPK1 |
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| Family | Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. |
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| Sequence | MDVVDPDIFNRDPRDHYDLLQRLGGGTYGEVFKARDKVSGDLVALKMVKMEPDDDVSTLQKEILILKTCRHANIVAYHGSYLWLQKLWICMEFCGAGSLQDIYQVTGSLSELQISYVCREVLQGLAYLHSQKKIHRDIKGANILINDAGEVRLADFGISAQIGATLARRLSFIGTPYWMAPEVAAVALKGGYNELCDIWSLGITAIELAELQPPLFDVHPLRVLFLMTKSGYQPPRLKEKGKWSAAFHNFIKVTLTKSPKKRPSATKMLSHQLVSQPGLNRGLILDLLDKLKNPGKGPSIGDIEDEEPELPPAIPRRIRSTHRSSSLGIPDADCCRRHMEFRKLRGMETRPPANTARLQPPRDLRSSSPRKQLSESSDDDYDDVDIPTPAEDTPPPLPPKPKFRSPSDEGPGSMGDDGQLSPGVLVRCASGPPPNSPRPGPPPSTSSPHLTAHSEPSLWNPPSRELDKPPLLPPKKEKMKRKGCALLVKLFNGCPLRIHSTAAWTHPSTKDQHLLLGAEEGIFILNRNDQEATLEMLFPSRTTWVYSINNVLMSLSGKTPHLYSHSILGLLERKETRAGNPIAHISPHRLLARKNMVSTKIQDTKGCRACCVAEGASSGGPFLCGALETSVVLLQWYQPMNKFLLVRQVLFPLPTPLSVFALLTGPGSELPAVCIGVSPGRPGKSVLFHTVRFGALSCWLGEMSTEHRGPVQVTQVEEDMVMVLMDGSVKLVTPEGSPVRGLRTPEIPMTEAVEAVAMVGGQLQAFWKHGVQVWALGSDQLLQELRDPTLTFRLLGSPRLECSGTISPHCNLLLPGSSNSPASASRVAGITGL Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 748652 | MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 9598 | VGNC:7488 | OMA, EggNOG |
| Mouse | 26411 | Map4k1 | mitogen-activated protein kinase kinase kinase kinase 1 | 10090 | MGI:1346882 | Inparanoid, OMA, EggNOG |
| Rat | 292763 | Map4k1 | mitogen activated protein kinase kinase kinase kinase 1 | 10116 | RGD:1305463 | Inparanoid, OMA, EggNOG |
| Dog | 484527 | MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 9615 | VGNC:42981 | Inparanoid, OMA, EggNOG |
| Horse | 100064279 | MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 9796 | VGNC:19945 | Inparanoid, OMA, EggNOG |
| Cow | 522002 | MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 9913 | VGNC:31204 | Inparanoid, OMA, EggNOG |
| Pig | 100516374 | MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 9823 | | OMA, EggNOG |
| Opossum | 100013272 | MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 13616 | | Inparanoid, OMA, EggNOG |
| Anole lizard | 100558628 | map4k1 | mitogen-activated protein kinase kinase kinase kinase 1 | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | 100216063 | map4k5 | mitogen-activated protein kinase kinase kinase kinase 5 | 8364 | XB-GENE-6037447 | OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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