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Protein or Target Summary

Mitogen-activated protein kinase kinase kinase kinase 1

Gene ID	11184
uniprot	Q92918
Gene Name	MAP4K1
Ensernbl ID	ENSP00000465039
Family	Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Sequence	MDVVDPDIFNRDPRDHYDLLQRLGGGTYGEVFKARDKVSGDLVALKMVKMEPDDDVSTLQKEILILKTCRHANIVAYHGSYLWLQKLWICMEFCGAGSLQDIYQVTGSLSELQISYVCREVLQGLAYLHSQKKIHRDIKGANILINDAGEVRLADFGISAQIGATLARRLSFIGTPYWMAPEVAAVALKGGYNELCDIWSLGITAIELAELQPPLFDVHPLRVLFLMTKSGYQPPRLKEKGKWSAAFHNFIKVTLTKSPKKRPSATKMLSHQLVSQPGLNRGLILDLLDKLKNPGKGPSIGDIEDEEPELPPAIPRRIRSTHRSSSLGIPDADCCRRHMEFRKLRGMETRPPANTARLQPPRDLRSSSPRKQLSESSDDDYDDVDIPTPAEDTPPPLPPKPKFRSPSDEGPGSMGDDGQLSPGVLVRCASGPPPNSPRPGPPPSTSSPHLTAHSEPSLWNPPSRELDKPPLLPPKKEKMKRKGCALLVKLFNGCPLRIHSTAAWTHPSTKDQHLLLGAEEGIFILNRNDQEATLEMLFPSRTTWVYSINNVLMSLSGKTPHLYSHSILGLLERKETRAGNPIAHISPHRLLARKNMVSTKIQDTKGCRACCVAEGASSGGPFLCGALETSVVLLQWYQPMNKFLLVRQVLFPLPTPLSVFALLTGPGSELPAVCIGVSPGRPGKSVLFHTVRFGALSCWLGEMSTEHRGPVQVTQVEEDMVMVLMDGSVKLVTPEGSPVRGLRTPEIPMTEAVEAVAMVGGQLQAFWKHGVQVWALGSDQLLQELRDPTLTFRLLGSPRLECSGTISPHCNLLLPGSSNSPASASRVAGITGL Show more

Gene and Protein Information

Species	Gene ID	Gene Symbol	Gene Name	Uniprot
HUMAN	11184	MAP4K1	Mitogen-activated protein kinase kinase kinase kinase 1	Q92918
MOUSE		Map4k1	Mitogen-activated protein kinase kinase kinase kinase	Q3UJX3
MOUSE	26411	Map4k1	Mitogen-activated protein kinase kinase kinase kinase	Q3UPT4
MOUSE		Map4k1	Mitogen activated protein kinase kinase kinase kinase 1, isoform CRA_a	A0A140LJF0
MOUSE	26411	Map4k1	Mitogen-activated protein kinase kinase kinase kinase 1	P70218
RAT	292763	Map4k1	Mitogen-activated protein kinase kinase kinase kinase	D3Z8I4

Protein Classes

DTO Classes
protein / Kinase / Protein kinase / STE group / STE20 family / KHS subfamily / Mitogen-activated protein kinase kinase kinase kinase 1

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

Source: DataSourcesLicenses.xlsx