NEK2

DescriptionSerine/threonine-protein kinase Nek2

Gene and Protein Information

Gene ID4751
Uniprot Accession IDs Q53FD6 Q5I1Z9 Q5VXZ1 Q6NZX8 Q7Z634 Q86XH2 Q96QN9
Ensembl ID ENSP00000355966
Symbol NEK2A NLK1 NLK1 RP67 NEK2A HsPK21 PPP1R111
FamilyBelongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
Sequence
MPSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILENPLIADLVADEQRRNLERRGRQLGEPEKSQDSSPVLSELKLKEIQLQERERALKAREERLEQKEQELCVRERLAEDKLARAENLLKNYSLLKERKFLSLASNPELLNLPSSVIKKKVHFSGESKENIMRSENSESQLTSKSKCKDLKKRLHAAQLRAQALSDIEKNYQLKSRQILGMR
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp457714NEK2NIMA related kinase 29598VGNC:6919OMA, EggNOG
Macaque711473NEK2NIMA related kinase 29544Inparanoid, OMA, EggNOG
Mouse18005Nek2NIMA (never in mitosis gene a)-related expressed kinase 210090MGI:109359Inparanoid, OMA, EggNOG
Rat114482Nek2NIMA-related kinase 210116RGD:619792OMA, EggNOG
Dog480021NEK2NIMA related kinase 29615VGNC:43731Inparanoid, OMA, EggNOG
Horse100054759NEK2NIMA related kinase 29796VGNC:20669Inparanoid, OMA, EggNOG
Cow523998NEK2NIMA related kinase 29913VGNC:31993Inparanoid, OMA, EggNOG
Pig397258NEK2NIMA related kinase 29823Inparanoid, OMA, EggNOG
Opossum100016325NEK2NIMA related kinase 213616Inparanoid, OMA, EggNOG
Platypus100078509NEK2NIMA related kinase 29258Inparanoid, OMA, EggNOG
Chicken421376NEK2NIMA related kinase 29031CGNC:7486Inparanoid, OMA, EggNOG
Anole lizard100565749nek2NIMA related kinase 228377Inparanoid, OMA, EggNOG
Xenopusnek2NIMA-related kinase 2 [Source:Xenbase;Acc:XB-GENE-962774]8364OMA, EggNOG
Zebrafish394025nek2NIMA-related kinase 27955ZDB-GENE-040426-752Inparanoid, EggNOG
S.cerevisiae851273KIN3serine/threonine protein kinase KIN34932S000000071Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    protein kinase    /    Serine/threonine-protein kinase nek2
protein    /    transferase    /    Serine/threonine-protein kinase nek2
protein    /    kinase    /    Serine/threonine-protein kinase nek2
DTO Classes
protein    /    Kinase    /    Protein kinase    /    Other group    /    NEK family    /    Serine/threonine-protein kinase nek2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source