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NEK4
| Description | Serine/threonine-protein kinase Nek4 |
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Gene and Protein Information
| Gene ID | 6787 |
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| Uniprot Accession IDs | A5YM70 B2R633 B7Z200 Q6P576 |
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| Ensembl ID | ENSP00000233027 |
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| Symbol | STK2 NRK2 STK2 pp12301 |
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| Family | Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily. |
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| Sequence | MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRTMLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAESNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELATISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQPENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQSLALSPKLECSGTILAHSNLRLLGSSDSPASASRVAGITGVCHHAQDQVAGECIIEKQGRIHPDLQPHNSGSEPSLSRQRRQKRREQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTGSVSSSRSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARRLSSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEINALVQLMTQTLKLDSKESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPSAIMPGSEKIRRLVEVLRTDVIRGLGVQLLEQVYDLLEEEDEFDREVRLREHMGEKYTTYSVKARQLKFFEENMNF Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Macaque | 695646 | NEK4 | NIMA related kinase 4 | 9544 | | OMA, EggNOG |
| Mouse | 23955 | Nek4 | NIMA (never in mitosis gene a)-related expressed kinase 4 | 10090 | MGI:1344404 | Inparanoid, OMA, EggNOG |
| Rat | 306252 | Nek4 | NIMA-related kinase 4 | 10116 | RGD:1304995 | Inparanoid, EggNOG |
| Dog | 476591 | NEK4 | NIMA related kinase 4 | 9615 | VGNC:43732 | Inparanoid, OMA, EggNOG |
| Horse | 100051545 | NEK4 | NIMA related kinase 4 | 9796 | VGNC:20671 | Inparanoid, OMA, EggNOG |
| Cow | 511455 | NEK4 | NIMA related kinase 4 | 9913 | VGNC:31995 | Inparanoid, OMA, EggNOG |
| Pig | 106504146 | NEK4 | NIMA related kinase 4 | 9823 | | Inparanoid, OMA, EggNOG |
| Opossum | 100020318 | NEK4 | NIMA related kinase 4 | 13616 | | Inparanoid, OMA, EggNOG |
| Platypus | | NEK4 | NIMA related kinase 4 [Source:HGNC Symbol;Acc:HGNC:11399] | 9258 | | OMA, EggNOG |
| Anole lizard | 100560174 | nek4 | NIMA related kinase 4 | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | 780225 | nek4 | NIMA-related kinase 4 | 8364 | XB-GENE-5914376 | Inparanoid, OMA, EggNOG |
| Zebrafish | 393987 | nek4 | NIMA-related kinase 4 | 7955 | ZDB-GENE-040426-1392 | Inparanoid, OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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