MAP3K14

DescriptionMitogen-activated protein kinase kinase kinase 14

Gene and Protein Information

Gene ID9020
Uniprot Accession IDs A8K2D8 D3DX67 Q8IYN1
Ensembl ID ENSP00000482657
Symbol NIK HS NIK HSNIK FTDCR1B
FamilyBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Sequence
MAVMEMACPGAPGSAVGQQKELPKAKEKTPPLGKKQSSVYKLEAVEKSPVFCGKWEILNDVITKGTAKEGSEAGPAAISIIAQAECENSQEFSPTFSERIFIAGSKQYSQSESLDQIPNNVAHATEGKMARVCWKGKRRSKARKKRKKKSSKSLAHAGVALAKPLPRTPEQESCTIPVQEDESPLGAPYVRNTPQFTKPLKEPGLGQLCFKQLGEGLRPALPRSELHKLISPLQCLNHVWKLHHPQDGGPLPLPTHPFPYSRLPHPFPFHPLQPWKPHPLESFLGKLACVDSQKPLPDPHLSKLACVDSPKPLPGPHLEPSCLSRGAHEKFSVEEYLVHALQGSVSSGQAHSLTSLAKTWAARGSRSREPSPKTEDNEGVLLTEKLKPVDYEYREEVHWATHQLRLGRGSFGEVHRMEDKQTGFQCAVKKVRLEVFRAEELMACAGLTSPRIVPLYGAVREGPWVNIFMELLEGGSLGQLVKEQGCLPEDRALYYLGQALEGLEYLHSRRILHGDVKADNVLLSSDGSHAALCDFGHAVCLQPDGLGKSLLTGDYIPGTETHMAPEVVLGRSCDAKVDVWSSCCMMLHMLNGCHPWTQFFRGPLCLKIASEPPPVREIPPSCAPLTAQAIQEGLRKEPIHRVSAAELGGKVNRALQQVGGLKSPWRGEYKEPRHPPPNQANYHQTLHAQPRELSPRAPGPRPAEETTGRAPKLQPPLPPEPPEPNKSPPLTLSKEESGMWEPLPLSSLEPAPARNPSSPERKATVPEQELQQLEIELFLNSLSQPFSLEEQEQILSCLSIDSLSLSDDSEKNPSKASQSSRDTLSSGVHSWSSQAEARSSSWNMVLARGRPTDTPSYFNGVKVQIQSLNGEHLHIREFHRVKVGDIATGISSQIPAAAFSLVTKDGQPVRYDMEVPDSGIDLQCTLAPDGSFAWSWRVKHGQLENRP
Show more
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque716258MAP3K14mitogen-activated protein kinase kinase kinase 149544Inparanoid, OMA
Mouse53859Map3k14mitogen-activated protein kinase kinase kinase 1410090MGI:1858204Inparanoid, OMA
Rat360640Map3k14mitogen-activated protein kinase kinase kinase 1410116RGD:1310487Inparanoid, OMA
Dog490926MAP3K14mitogen-activated protein kinase kinase kinase 149615VGNC:42970Inparanoid, OMA
Horse100050140MAP3K14mitogen-activated protein kinase kinase kinase 149796VGNC:19933Inparanoid, OMA
Cow508367MAP3K14mitogen-activated protein kinase kinase kinase 149913VGNC:31192Inparanoid, OMA
Pig100520402MAP3K14mitogen-activated protein kinase kinase kinase 149823Inparanoid, OMA
Chicken419964MAP3K14mitogen-activated protein kinase kinase kinase 149031CGNC:434Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    STE group    /    STE-UNIQUE family    /    Mitogen-activated protein kinase kinase kinase 14

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source