NEDD4

DescriptionE3 ubiquitin-protein ligase NEDD4

Gene and Protein Information

Gene ID4734
Uniprot Accession IDs A1KY35 A6ND72 A7MD29 B4E2R7 B7ZM59 B7ZM60 B9EGN5 D6RF89
Ensembl ID ENSP00000424827
Symbol KIAA0093 NEDD4-1 RPF1 NEDD4-1
Sequence
MAQSLRLHFAARRSNTYPLSETSGDDLDSHVHMCFKRPTRISTSNVVQMKLTPRQTALAPLIKENVQSQERSSVPSSENVNKKSSCLQISLQPTRYSGYLQSSNVLADSDDASFTCILKDGIYSSAVVDNELNAVNDGHLVSSPAICSGSLSNFSTSDNGSYSSNGSDFGSCASITSGGSYTNSVISDSSSYTFPPSDDTFLGGNLPSDSTSNRSVPNRNTTPCEIFSRSTSTDPFVQDDLEHGLEIMKLPVSRNTKIPLKRYSSLVIFPRSPSTTRPTSPTSLCTLLSKGSYQTSHQFIISPSEIAHNEDGTSAKGFLSTAVNGLRLSKTICTPGEVRDIRPLHRKGSLQKKIVLSNNTPRQTVCEKSSEGYSCVSVHFTQRKAATLDCETTNGDCKPEMSEIKLNSDSEYIKLMHRTSACLPSSQNVDCQININGELERPHSQMNKNHGILRRSISLGGAYPNISCLSSLKHNCSKGGPSQLLIKFASGNEGKVDNLSRDSNRDCTNELSNSCKTRDDFLGQVDVPLYPLPTENPRLERPYTFKDFVLHPRSHKSRVKGYLRLKMTYLPKTSGSEDDNAEQAEELEPGWVVLDQPDAACHLQQQQEPSPLPPGWEERQDILGRTYYVNHESRRTQWKRPTPQDNLTDAENGNIQLQAQRAFTTRRQISEETESVDNRESSENWEIIREDEATMYSNQAFPSPPPSSNLDVPTHLAEELNARLTIFGNSAVSQPASSSNHSSRRGSLQAYTFEEQPTLPVLLPTSSGLPPGWEEKQDERGRSYYVDHNSRTTTWTKPTVQATVETSQLTSSQSSAGPQSQASTSDSGQQVTQPSEIEQGFLPKGWEVRHAPNGRPFFIDHNTKTTTWEDPRLKIPAHLRGKTSLDTSNDLGPLPPGWEERTHTDGRIFYINHNIKRTQWEDPRLENVAITGPAVPYSRDYKRKYEFFRRKLKKQNDIPNKFEMKLRRATVLEDSYRRIMGVKRADFLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLHKPITLHDMESVDSEYYNSLRWILENDPTELDLRFIIDEELFGQTHQHELKNGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGDVDVNDWREHTKYKNGYSANHQVIQWFWKAVLMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQWGTPEKLPRAHTCFNRLDLPPYESFEELWDKLQMAIENTQGFDGVD
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque699550NEDD4neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase9544Inparanoid, OMA, EggNOG
Mouse17999Nedd4neural precursor cell expressed, developmentally down-regulated 410090MGI:97297Inparanoid, OMA, EggNOG
Rat25489Nedd4neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase10116RGD:3157Inparanoid, OMA
Dog608738NEDD4neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase9615Inparanoid, EggNOG
Horse100054735NEDD4neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase9796VGNC:20659Inparanoid, OMA, EggNOG
Opossum100020178NEDD4neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase13616Inparanoid, EggNOG
Platypus100083335NEDD4neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase9258Inparanoid, OMA, EggNOG
Chicken415406NEDD4neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase9031CGNC:3198Inparanoid, OMA
Xenopus100496333nedd4neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase8364XB-GENE-478443Inparanoid, OMA, EggNOG
Fruitfly39958Nedd4CG42279 gene product from transcript CG42279-RJ7227FBgn0259174Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    ligase    /    ubiquitin-protein ligase    /    E3 ubiquitin-protein ligase NEDD4
DTO Classes
protein    /    Enzyme    /    Ligase    /    Ubiquitin-protein ligase    /    E3 ubiquitin-protein ligase NEDD4

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source