MAN2B1

DescriptionLysosomal alpha-mannosidase

Gene and Protein Information

Gene ID4125
Uniprot Accession IDs G5E928 O15330 Q16680 Q93094 Q9BW13 Laman
Ensembl ID ENSP00000395473
Symbol LAMAN MANB MANB LAMAN
FamilyBelongs to the glycosyl hydrolase 38 family.
Sequence
MGAYARASGVCARGCLDSAGPWTMSRALRPPLPPLCFFLLLLAAAGARAGGYETCPTVQPNMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVEIAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFLNVATAQGRYYRTNHTVMTMGSDFQYENANMWFKNLDKLIRLVNAQQAKGSSVHVLYSTPACYLWELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVGLAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNALARLRGFKDHFTFCQQLNISICPLSQTAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDPNGRTVPSDVVIFPSSDSQAHPPELLFSASLPALGFSTYSVAQVPRWKPQARAPQPIPRRSWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAYIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVANQLREAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTFLASVQWKEVDG
Show more
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp455745MAN2B1mannosidase alpha class 2B member 19598OMA, EggNOG
MacaqueWDR83OSprotein Asterix [Source:RefSeq peptide;Acc:NP_001181335]9544OMA, EggNOG
Mouse17159Man2b1mannosidase 2, alpha B110090MGI:107286Inparanoid, OMA, EggNOG
Rat361378Man2b1mannosidase, alpha, class 2B, member 110116RGD:3039Inparanoid, OMA, EggNOG
Dog484932MAN2B1mannosidase alpha class 2B member 19615Inparanoid, OMA, EggNOG
Horse100064359MAN2B1mannosidase alpha class 2B member 19796Inparanoid, OMA, EggNOG
Cow282272MAN2B1mannosidase alpha class 2B member 19913Inparanoid, OMA, EggNOG
Pig100518647MAN2B1mannosidase alpha class 2B member 19823OMA, EggNOG
Opossum100010377MAN2B1mannosidase alpha class 2B member 113616Inparanoid, OMA, EggNOG
Anole lizard100557773man2b1mannosidase alpha class 2B member 128377OMA, EggNOG
Xenopus779924man2b1mannosidase, alpha, class 2B, member 18364XB-GENE-958698Inparanoid, OMA, EggNOG
Zebrafish541519man2b1mannosidase, alpha, class 2B, member 17955ZDB-GENE-050327-52Inparanoid, OMA
C. elegans180749aman-1Alpha-mannosidase6239Inparanoid, OMA

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source