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MAP4K3
| Description | Mitogen-activated protein kinase kinase kinase kinase 3 |
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Gene and Protein Information
| Gene ID | 8491 |
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| Uniprot Accession IDs | Q6IQ39 Q8IVH7 Q9UDM5 Q9Y6R5 |
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| Ensembl ID | ENSP00000263881 |
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| Symbol | RAB8IPL1 GLK MEKKK3 MEKKK 3 MAPKKKK3 RAB8IPL1 |
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| Family | Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. |
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| Sequence | MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVTQHLTRSLAIELLDKVNNPDHSTYHDFDDDDPEPLVAVPHRIHSTSRNVREEKTRSEITFGQVKFDPPLRKETEPHHELPDSDGFLDSSEEIYYTARSNLDLQLEYGQGHQGGYFLGANKSLLKSVEEELHQRGHVAHLEDDEGDDDESKHSTLKAKIPPPLPPKPKSIFIPQEMHSTEDENQGTIKRCPMSGSPAKPSQVPPRPPPPRLPPHKPVALGNGMSSFQLNGERDGSLCQQQNEHRGTNLSRKEKKDVPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCASSWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCLLSISGKASQLYSHNLPGLFDYARQMQKLPVAIPAHKLPDRILPRKFSVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEPMQKFMLIKHIDFPIPCPLRMFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVNPNSTSSWFTESDTPQTNVTHVTQLERDTILVCLDCCIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQGRSFRSNEVTQEISDSTRIFRLLGSDRVVVLESRPTDNPTANSNLYILAGHENSY Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 459173 | MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 9598 | VGNC:300 | OMA, EggNOG |
| Macaque | 713952 | MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 9544 | | OMA, EggNOG |
| Mouse | 225028 | Map4k3 | mitogen-activated protein kinase kinase kinase kinase 3 | 10090 | MGI:2154405 | Inparanoid, OMA, EggNOG |
| Rat | 170920 | Map4k3 | mitogen-activated protein kinase kinase kinase kinase 3 | 10116 | RGD:621280 | Inparanoid, OMA, EggNOG |
| Dog | 475734 | MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 9615 | VGNC:42983 | Inparanoid, OMA |
| Horse | 100069835 | MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 9796 | VGNC:19947 | Inparanoid, OMA |
| Cow | 507624 | MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 9913 | VGNC:31206 | Inparanoid, OMA |
| Opossum | 100010710 | MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 13616 | | Inparanoid, EggNOG |
| Platypus | 100078832 | MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 9258 | | Inparanoid, OMA, EggNOG |
| Anole lizard | 100559042 | map4k3 | mitogen-activated protein kinase kinase kinase kinase 3 | 28377 | | Inparanoid, OMA |
| Xenopus | 100170570 | map4k3 | mitogen-activated protein kinase kinase kinase kinase 3 | 8364 | XB-GENE-951441 | Inparanoid, OMA |
| C. elegans | 179072 | gck-2 | Mitogen-activated protein kinase kinase kinase kinase | 6239 | | OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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