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Protein or Target Summary

Mitogen-activated protein kinase kinase kinase kinase 4

Gene ID	9448
uniprot	O95819
Gene Name	MAP4K4
Ensernbl ID	ENSP00000343658
Family	Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Sequence	MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNHSSPEAQSKQTGRVLEPPVPSRSESFSNGNSESVHPALQRPAEPQVPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNSTSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPADLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW Show more

Gene and Protein Information

Species	Gene ID	Gene Symbol	Gene Name	Uniprot
HUMAN	9448	MAP4K4	Mitogen-activated protein kinase kinase kinase kinase 4	O95819
MOUSE	26921	Map4k4	Uncharacterized protein	Q3UTY9
MOUSE	26921	Map4k4	Map4k4 protein	B7ZNR8
MOUSE		Map4k4	Mitogen-activated protein kinase kinase kinase kinase 4	A0A0A6YWJ2
MOUSE		Map4k4	Mitogen-activated protein kinase kinase kinase kinase 4	A0A0A6YVR7
MOUSE		Map4k4	Mitogen-activated protein kinase kinase kinase kinase 4	E9PVG7
MOUSE	26921	Map4k4	Mitogen-activated protein kinase kinase kinase kinase 4	A0A0A6YW53
MOUSE		Map4k4	Mitogen-activated protein kinase kinase kinase kinase 4	A0A0A6YXE5
MOUSE	26921	Map4k4	Mitogen-activated protein kinase kinase kinase kinase 4	A0A0A6YWM8
MOUSE	26921	Map4k4	Mitogen-activated protein kinase kinase kinase kinase 4	A0A0A6YWR8
MOUSE		Map4k4	Mitogen-activated protein kinase kinase kinase kinase 4	A0A0A6YVZ8
MOUSE	26921	Map4k4	Mitogen-activated protein kinase kinase kinase kinase 4	F8VPL5
MOUSE	26921	Map4k4	Map4k4 protein	B2RUE8
MOUSE	26921	Map4k4	Map4k4 protein	B7ZNR9
MOUSE	26921	Map4k4	Mitogen-activated protein kinase kinase kinase kinase 4	P97820
RAT		Map4k4	Mitogen-activated protein kinase kinase kinase kinase 4	A0A0G2K7W4
RAT		Map4k4	Mitogen-activated protein kinase kinase kinase kinase 4	A0A097PIG6
RAT	301363	Map4k4	Mitogen-activated protein kinase kinase kinase kinase 4	F1M754

Protein Classes

DTO Classes
protein / Kinase / Protein kinase / STE group / STE20 family / MSN subfamily / Mitogen-activated protein kinase kinase kinase kinase 4

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

Source: TCRDv6_DataSourcesLicenses.xlsx