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MAP4K4

Description	Mitogen-activated protein kinase kinase kinase kinase 4

Gene and Protein Information

Gene ID	9448
Uniprot Accession IDs	E7ESS2 O75172 Q9NST7
Ensembl ID	ENSP00000343658
Symbol	HGK KIAA0687 NIK HGK NIK MEKKK4 FLH21957 HEL-S-31
Family	Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Sequence	MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNHSSPEAQSKQTGRVLEPPVPSRSESFSNGNSESVHPALQRPAEPQVPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNSTSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPADLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	459459	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	9598	VGNC:299	Inparanoid, OMA, EggNOG
Macaque	716595	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	9544		Inparanoid, OMA
Mouse	26921	Map4k4	mitogen-activated protein kinase kinase kinase kinase 4	10090	MGI:1349394	Inparanoid, OMA, EggNOG
Rat	301363	Map4k4	mitogen-activated protein kinase kinase kinase kinase 4	10116	RGD:1305322	Inparanoid, OMA, EggNOG
Dog	481331	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	9615	VGNC:42984	Inparanoid, OMA
Horse	100058919	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	9796	VGNC:19948	Inparanoid, OMA
Opossum	100017539	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	13616		Inparanoid, OMA
Anole lizard	100567473	map4k4	mitogen-activated protein kinase kinase kinase kinase 4	28377		Inparanoid, OMA

Protein Classes

DTO Classes
protein / Kinase / Protein kinase / STE group / STE20 family / MSN subfamily / Mitogen-activated protein kinase kinase kinase kinase 4

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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