MAP3K11

DescriptionMitogen-activated protein kinase kinase kinase 11

Gene and Protein Information

Gene ID4296
Uniprot Accession IDs B4DS76 Q53H00 Q59F06 Q6P2G4
Ensembl ID ENSP00000309597
Symbol MLK3 PTK1 SPRK MLK3 PTK1 SPRK MLK-3 MEKK11
FamilyBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Sequence
MEPLKSLFLKSPLGSWNGSGSGGGGGGGGGRPEGSPKAAGYANPVWTALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVGGQVGIFPSNYVSRGGGPPPCEVASFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIESDDMEHKTLKITDFGLAREWHKTTQMSAAGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLREMPRDSFHSMQEGWKREIQGLFDELRAKEKELLSREEELTRAAREQRSQAEQLRRREHLLAQWELEVFERELTLLLQQVDRERPHVRRRRGTFKRSKLRARDGGERISMPLDFKHRITVQASPGLDRRRNVFEVGPGDSPTFPRFRAIQLEPAEPGQAWGRQSPRRLEDSSNGERRACWAWGPSSPKPGEAQNGRRRSRMDEATWYLDSDDSSPLGSPSTPPALNGNPPRPSLEPEEPKRPVPAERGSSSGTPKLIQRALLRGTALLASLGLGRDLQPPGGPGRERGESPTTPPTPTPAPCPTEPPPSPLICFSLKTPDSPPTPAPLLLDLGIPVGQRSAKSPRREEEPRGGTVSPPPGTSRSAPGTPGTPRSPPLGLISRPRPSPLRSRIDPWSFVSAGPRPSPLPSPQPAPRRAPWTLFPDSDPFWDSPPANPFQGGPQDCRAQTKDMGAQAPWVPEAGP
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp451326MAP3K11mitogen-activated protein kinase kinase kinase 119598VGNC:11916OMA, EggNOG
Mouse26403Map3k11mitogen-activated protein kinase kinase kinase 1110090MGI:1346880Inparanoid, OMA, EggNOG
Rat309168Map3k11mitogen-activated protein kinase kinase kinase 1110116RGD:1359261Inparanoid, OMA, EggNOG
Dog483732MAP3K11mitogen-activated protein kinase kinase kinase 119615VGNC:42967Inparanoid, OMA, EggNOG
HorseMAP3K11mitogen-activated protein kinase kinase kinase 11 [Source:HGNC Symbol;Acc:HGNC:6850]9796OMA, EggNOG
Cow514210MAP3K11mitogen-activated protein kinase kinase kinase 119913VGNC:31189Inparanoid, OMA, EggNOG
Opossum100030111MAP3K11mitogen-activated protein kinase kinase kinase 1113616Inparanoid, OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    MLK family    /    MLK subfamily    /    Mitogen-activated protein kinase kinase kinase 11

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source