ABCC5

DescriptionMultidrug resistance-associated protein 5

Gene and Protein Information

Gene ID10057
Uniprot Accession IDs B9EIQ2 O14517 Q29ZA9 Q29ZB1 Q86UX3 Q86W30 Q9UN85 Q9UNP5 Q9UQC3
Ensembl ID ENSP00000333926
Symbol MRP5 MRP5 SMRP ABC33 MOATC MOAT-C pABC11 EST277145
FamilyBelongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Sequence
MKDIDIGKEYIIPSPGYRSVRERTSTSGTHRDREDSKFRRTRPLECQDALETAARAEGLSLDASMHSQLRILDEEHPKGKYHHGLSALKPIRTTSKHQHPVDNAGLFSCMTFSWLSSLARVAHKKGELSMEDVWSLSKHESSDVNCRRLERLWQEELNEVGPDAASLRRVVWIFCRTRLILSIVCLMITQLAGFSGPAFMVKHLLEYTQATESNLQYSLLLVLGLLLTEIVRSWSLALTWALNYRTGVRLRGAILTMAFKKILKLKNIKEKSLGELINICSNDGQRMFEAAAVGSLLAGGPVVAILGMIYNVIILGPTGFLGSAVFILFYPAMMFASRLTAYFRRKCVAATDERVQKMNEVLTYIKFIKMYAWVKAFSQSVQKIREEERRILEKAGYFQSITVGVAPIVVVIASVVTFSVHMTLGFDLTAAQAFTVVTVFNSMTFALKVTPFSVKSLSEASVAVDRFKSLFLMEEVHMIKNKPASPHIKIEMKNATLAWDSSHSSIQNSPKLTPKMKKDKRASRGKKEKVRQLQRTEHQAVLAEQKGHLLLDSDERPSPEEEEGKHIHLGHLRLQRTLHSIDLEIQEGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAISGTFAYVAQQAWILNATLRDNILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGANLSGGQRQRISLARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSKTVLFVTHQLQYLVDCDEVIFMKEGCITERGTHEELMNLNGDYATIFNNLLLGETPPVEINSKKETSGSQKKSQDKGPKTGSVKKEKAVKPEEGQLVQLEEKGQGSVPWSVYGVYIQAAGGPLAFLVIMALFMLNVGSTAFSTWWLSYWIKQGSGNTTVTRGNETSVSDSMKDNPHMQYYASIYALSMAVMLILKAIRGVVFVKGTLRASSRLHDELFRRILRSPMKFFDTTPTGRILNRFSKDMDEVDVRLPFQAEMFIQNVILVFFCVGMIAGVFPWFLVAVGPLVILFSVLHIVSRVLIRELKRLDNITQSPFLSHITSSIQGLATIHAYNKGQEFLHRYQELLDDNQAPFFLFTCAMRWLAVRLDLISIALITTTGLMIVLMHGQIPPAYAGLAISYAVQLTGLFQFTVRLASETEARFTSVERINHYIKTLSLEAPARIKNKAPSPDWPQEGEVTFENAEMRYRENLPLVLKKVSFTIKPKEKIGIVGRTGSGKSSLGMALFRLVELSGGCIKIDGVRISDIGLADLRSKLSIIPQEPVLFSGTVRSNLDPFNQYTEDQIWDALERTHMKECIAQLPLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDTETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLSNDSSRFYAMFAAAENKVAVKG
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque704326ABCC5ATP binding cassette subfamily C member 59544Inparanoid, OMA, EggNOG
Mouse27416Abcc5ATP-binding cassette, sub-family C (CFTR/MRP), member 510090MGI:1351644Inparanoid, OMA, EggNOG
Rat116721Abcc5ATP binding cassette subfamily C member 510116RGD:70913Inparanoid, OMA, EggNOG
Dog478648ABCC5ATP binding cassette subfamily C member 59615VGNC:37442Inparanoid, OMA, EggNOG
Horse100066941ABCC5ATP binding cassette subfamily C member 59796VGNC:14920Inparanoid, OMA, EggNOG
Cow511769ABCC5ATP binding cassette subfamily C member 59913VGNC:25474OMA, EggNOG
Pig100513626ABCC5ATP binding cassette subfamily C member 59823OMA, EggNOG
Opossum100011713ABCC5ATP binding cassette subfamily C member 513616Inparanoid, OMA, EggNOG
Platypus100073452ABCC5ATP binding cassette subfamily C member 59258Inparanoid, OMA, EggNOG
Chicken424947ABCC5ATP binding cassette subfamily C member 59031CGNC:6342Inparanoid, EggNOG
Anole lizard100566117abcc5ATP binding cassette subfamily C member 528377Inparanoid, OMA, EggNOG
Zebrafish336147abcc5ATP-binding cassette, sub-family C (CFTR/MRP), member 57955ZDB-GENE-050517-17Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transporter    /    ATP-binding cassette (ABC) transporter    /    Multidrug resistance-associated protein 5
DTO Classes
protein    /    Transporter    /    ATP-binding cassette transporter family    /    ABCC subfamily    /    Multidrug resistance-associated protein 5

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source