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JAK1
| Description | Tyrosine-protein kinase JAK1 |
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Gene and Protein Information
| Gene ID | 3716 |
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| Uniprot Accession IDs | Q59GQ2 Q9UD26 |
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| Ensembl ID | ENSP00000343204 |
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| Symbol | JAK1A JAK1B JTK3 JAK1A JAK1B |
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| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily. |
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| Sequence | MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEELCIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTNDNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQDGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRINNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMNWFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIREEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTCFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFMLKRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSGTLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGTTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 743373 | JAK1 | Janus kinase 1 | 9598 | VGNC:1281 | OMA, EggNOG |
| Macaque | 677689 | JAK1 | Janus kinase 1 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 16451 | Jak1 | Janus kinase 1 | 10090 | MGI:96628 | Inparanoid, OMA, EggNOG |
| Rat | 84598 | Jak1 | Janus kinase 1 | 10116 | RGD:69056 | Inparanoid, OMA, EggNOG |
| Dog | 442952 | JAK1 | Janus kinase 1 | 9615 | VGNC:42175 | Inparanoid, OMA, EggNOG |
| Horse | 100054008 | JAK1 | Janus kinase 1 | 9796 | VGNC:19212 | Inparanoid, OMA, EggNOG |
| Cow | 537201 | JAK1 | Janus kinase 1 | 9913 | VGNC:30364 | Inparanoid, OMA, EggNOG |
| Chicken | 395681 | JAK1 | Janus kinase 1 | 9031 | CGNC:8381 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100559328 | jak1 | Janus kinase 1 | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | 100038172 | jak1 | Janus kinase 1 (a protein tyrosine kinase) | 8364 | XB-GENE-483750 | Inparanoid, OMA, EggNOG |
| Zebrafish | 30280 | jak1 | Janus kinase 1 | 7955 | ZDB-GENE-980526-142 | Inparanoid, OMA |
| Fruitfly | 32080 | hop | hopscotch | 7227 | FBgn0004864 | OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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