CDC42BPA

Description	Serine/threonine-protein kinase MRCK alpha

Gene and Protein Information

Gene ID	8476
Uniprot Accession IDs	O75039 Q59GZ1 Q5H9N9 Q5T797 Q5VT26 Q5VT27 Q86XX2 Q86XX3 Q99646
Ensembl ID	ENSP00000355731
Symbol	KIAA0451 MRCK MRCKA PK428
Family	Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
Sequence	MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTAGPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQALASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEELNKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTPTDALDQFERSPSCTPASKGRRTVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPASPRKTKSLSLESTDRGSWDP Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Macaque	697811	CDC42BPA	CDC42 binding protein kinase alpha	9544		Inparanoid, OMA, EggNOG
Mouse	226751	Cdc42bpa	CDC42 binding protein kinase alpha	10090	MGI:2441841	Inparanoid, OMA, EggNOG
Rat	114116	Cdc42bpa	CDC42 binding protein kinase alpha	10116	RGD:621406	Inparanoid, OMA, EggNOG
Dog	480107	CDC42BPA	CDC42 binding protein kinase alpha	9615	VGNC:38997	Inparanoid, OMA, EggNOG
Horse	100054548	CDC42BPA	CDC42 binding protein kinase alpha	9796	VGNC:16296	Inparanoid, OMA, EggNOG
Cow	538392	CDC42BPA	CDC42 binding protein kinase alpha	9913	VGNC:27069	Inparanoid, OMA, EggNOG
Pig	100511216	CDC42BPA	CDC42 binding protein kinase alpha	9823		OMA, EggNOG
Opossum	100019700	CDC42BPA	CDC42 binding protein kinase alpha	13616		Inparanoid, OMA, EggNOG
Platypus		CDC42BPA	CDC42 binding protein kinase alpha [Source:HGNC Symbol;Acc:HGNC:1737]	9258		OMA, EggNOG
Chicken	416746	CDC42BPA	CDC42 binding protein kinase alpha	9031	CGNC:6969	Inparanoid, OMA, EggNOG
Anole lizard	100566985	cdc42bpa	CDC42 binding protein kinase alpha	28377		Inparanoid, OMA, EggNOG
Xenopus		cdc42bpa	CDC42 binding protein kinase alpha [Source:Xenbase;Acc:XB-GENE-6037508]	8364		OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    non-receptor serine/threonine protein kinase    /    Serine/threonine-protein kinase mrck alpha
protein    /    protein kinase    /    Serine/threonine-protein kinase mrck alpha
protein    /    transferase    /    Serine/threonine-protein kinase mrck alpha
protein    /    kinase    /    Serine/threonine-protein kinase mrck alpha

DTO Classes
protein / Kinase / Protein kinase / AGC group / DMPK family / GEK subfamily / Serine/threonine-protein kinase mrck alpha

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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