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POLA1
| Description | DNA polymerase alpha catalytic subunit |
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Gene and Protein Information
| Gene ID | 5422 |
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| Uniprot Accession IDs | Q86UQ7 |
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| Ensembl ID | ENSP00000368349 |
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| Symbol | POLA NSX POLA p180 |
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| Family | Belongs to the DNA polymerase type-B family. |
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| Sequence | MAPVHGDDSLSDSGSFVSSRARREKKSKKGRQEALERLKKAKAGEKYKYEVEDFTGVYEEVDEEQYSKLVQARQDDDWIVDDDGIGYVEDGREIFDDDLEDDALDADEKGKDGKARNKDKRNVKKLAVTKPNNIKSMFIACAGKKTADKAVDLSKDGLLGDILQDLNTETPQITPPPVMILKKKRSIGASPNPFSVHTATAVPSGKIASPVSRKEPPLTPVPLKRAEFAGDDVQVESTEEEQESGAMEFEDGDFDEPMEVEEVDLEPMAAKAWDKESEPAEEVKQEADSGKGTVSYLGSFLPDVSCWDIDQEGDSSFSVQEVQVDSSHLPLVKGADEEQVFHFYWLDAYEDQYNQPGVVFLFGKVWIESAETHVSCCVMVKNIERTLYFLPREMKIDLNTGKETGTPISMKDVYEEFDEKIATKYKIMKFKSKPVEKNYAFEIPDVPEKSEYLEVKYSAEMPQLPQDLKGETFSHVFGTNTSSLELFLMNRKIKGPCWLEVKSPQLLNQPVSWCKVEAMALKPDLVNVIKDVSPPPLVVMAFSMKTMQNAKNHQNEIIAMAALVHHSFALDKAAPKPPFQSHFCVVSKPKDCIFPYAFKEVIEKKNVKVEVAATERTLLGFFLAKVHKIDPDIIVGHNIYGFELEVLLQRINVCKAPHWSKIGRLKRSNMPKLGGRSGFGERNATCGRMICDVEISAKELIRCKSYHLSELVQQILKTERVVIPMENIQNMYSESSQLLYLLEHTWKDAKFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRKPQQKLGDEDEEIDGDTNKYKKGRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRVASEAQKVTEDGEQEQIPELPDPSLEMGILPREIRKLVERRKQVKQLMKQQDLNPDLILQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREILMHTKEMVQKMNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALVVEPTSDGNYVTKQELKGLDIVRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDKKSLPHVHVALWINSQGGRKVKAGDTVSYVICQDGSNLTASQRAYAPEQLQKQDNLTIDTQYYLAQQIHPVVARICEPIDGIDAVLIATWLGLDPTQFRVHHYHKDEENDALLGGPAQLTDEEKYRDCERFKCPCPTCGTENIYDNVFDGSGTDMEPSLYRCSNIDCKASPLTFTVQLSNKLIMDIRRFIKKYYDGWLICEEPTCRNRTRHLPLQFSRTGPLCPACMKATLQPEYSDKSLYTQLCFYRYIFDAECALEKLTTDHEKDKLKKQFFTPKVLQDYRKLKNTAEQFLSRSGYSEVNLSKLFAGCAVKS Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 100611187 | POLA1 | DNA polymerase alpha 1, catalytic subunit | 9598 | VGNC:8330 | OMA, EggNOG |
| Macaque | 699763 | POLA1 | DNA polymerase alpha 1, catalytic subunit | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 18968 | Pola1 | polymerase (DNA directed), alpha 1 | 10090 | MGI:99660 | Inparanoid, OMA, EggNOG |
| Rat | 85241 | Pola1 | DNA polymerase alpha 1, catalytic subunit | 10116 | RGD:621816 | Inparanoid, OMA, EggNOG |
| Dog | 480869 | POLA1 | DNA polymerase alpha 1, catalytic subunit | 9615 | VGNC:44771 | Inparanoid, OMA, EggNOG |
| Horse | 100052225 | POLA1 | DNA polymerase alpha 1, catalytic subunit | 9796 | VGNC:21649 | Inparanoid, OMA, EggNOG |
| Cow | 534848 | POLA1 | DNA polymerase alpha 1, catalytic subunit | 9913 | VGNC:33110 | Inparanoid, OMA, EggNOG |
| Opossum | 100011328 | POLA1 | DNA polymerase alpha 1, catalytic subunit | 13616 | | Inparanoid, OMA, EggNOG |
| Chicken | 418593 | POLA1 | DNA polymerase alpha 1, catalytic subunit | 9031 | CGNC:12201 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100553905 | pola1 | DNA polymerase alpha 1, catalytic subunit | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | 100379926 | pola1 | polymerase (DNA directed), alpha 1, catalytic subunit | 8364 | XB-GENE-1000548 | Inparanoid, OMA, EggNOG |
| Zebrafish | 317740 | pola1 | polymerase (DNA directed), alpha 1 | 7955 | ZDB-GENE-030114-9 | Inparanoid, OMA, EggNOG |
| C. elegans | 176544 | pola-1 | DNA polymerase | 6239 | | OMA, EggNOG |
| Fruitfly | 42553 | DNApol-alpha180 | DNA polymerase alpha 180kD | 7227 | FBgn0259113 | Inparanoid, OMA, EggNOG |
| S.cerevisiae | 855621 | POL1 | DNA-directed DNA polymerase alpha catalytic subunit POL1 | 4932 | S000005046 | Inparanoid, OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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