ABCC4

Description	Multidrug resistance-associated protein 4

Gene and Protein Information

Gene ID	10257
Uniprot Accession IDs	A9Z1Z7 B7Z3Q7 Q8IVZ4 Q8IZN6 Q8NEW8 Q9Y6J2
Ensembl ID	ENSP00000366084
Symbol	MRP4 MRP4 MOATB MOAT-B
Family	Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Sequence	MLPVYQEVKPNPLQDANLCSRVFFWWLNPLFKIGHKRRLEEDDMYSVLPEDRSQHLGEELQGFWDKEVLRAENDAQKPSLTRAIIKCYWKSYLVLGIFTLIEESAKVIQPIFLGKIINYFENYDPMDSVALNTAYAYATVLTFCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFDQVTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPLQSCFGKLFSSLRSKTATFTDARIRTMNEVITGIRIIKMYAWEKSFSNLITNLRKKEISKILRSSCLRGMNLASFFSASKIIVFVTFTTYVLLGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRIQTFLLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEESEQPPVPGTPTLRNRTFSESSVWSQQSSRPSLKDGALESQDTENVPVTLSEENRSEGKVGFQAYKNYFRAGAHWIVFIFLILLNTAAQVAYVLQDWWLSYWANKQSMLNVTVNGGGNVTEKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMFVIIVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEYTDLEKEAPWEYQKRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNKESLFYKMVQQLGKAEAAALTETAKQVYFKRNYPHIGHTDHMVTNTSNGQPSTLTIFETAL Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	452625	ABCC4	ATP binding cassette subfamily C member 4	9598	VGNC:13060	OMA, EggNOG
Macaque	695407	LOC695407	multidrug resistance-associated protein 4	9544		OMA, EggNOG
Mouse	239273	Abcc4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	10090	MGI:2443111	Inparanoid, OMA, EggNOG
Rat	170924	Abcc4	ATP binding cassette subfamily C member 4	10116	RGD:620266	Inparanoid, OMA, EggNOG
Dog	485523	ABCC4	ATP binding cassette subfamily C member 4	9615	VGNC:37441	Inparanoid, OMA, EggNOG
Horse	100050431	ABCC4	ATP binding cassette subfamily C member 4	9796	VGNC:14919	Inparanoid, OMA, EggNOG
Cow	515333	LOC515333	multidrug resistance-associated protein 4	9913		OMA, EggNOG
Pig	100738425	LOC100738425	multidrug resistance-associated protein 4	9823		OMA, EggNOG
Opossum	100027089	ABCC4	ATP binding cassette subfamily C member 4	13616		Inparanoid, OMA, EggNOG
Platypus		ABCC4	ATP binding cassette subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:55]	9258		OMA, EggNOG
Chicken	418791	ABCC4	ATP binding cassette subfamily C member 4	9031	CGNC:12680	Inparanoid, OMA, EggNOG
Anole lizard	100558731	abcc4	ATP binding cassette subfamily C member 4	28377		Inparanoid, OMA, EggNOG
Xenopus		abcc4	ATP binding cassette subfamily C member 4 [Source:Xenbase;Acc:XB-GENE-957302]	8364		OMA, EggNOG
Zebrafish	368620	abcc4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	7955	ZDB-GENE-030616-511	Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein / transporter / ATP-binding cassette (ABC) transporter / Multidrug resistance-associated protein 4

DTO Classes
protein / Transporter / ATP-binding cassette transporter family / ABCC subfamily / Multidrug resistance-associated protein 4

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source