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MAP3K5
| Description | Mitogen-activated protein kinase kinase kinase 5 |
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Gene and Protein Information
| Gene ID | 4217 |
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| Uniprot Accession IDs | A6NIA0 B4DGB2 Q5THN3 Q99461 |
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| Ensembl ID | ENSP00000351908 |
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| Symbol | ASK1 MAPKKK5 MEKK5 ASK1 MEKK5 MAPKKK5 |
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| Family | Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. |
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| Sequence | MSTEADEGITFSVPPFAPSGFCTIPEGGICRRGGAAAVGEGEEHQLPPPPPGSFWNVESAAAPGIGCPAATSSSSATRGRGSSVGGGSRRTTVAYVINEASQGQLVVAESEALQSLREACETVGATLETLHFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMYCLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLPVPVLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKSQPIEIPELPVFHLNSSGTNTEDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDDLKCLRLRGGMLCTLWKAIIDFRNKQT Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 463023 | MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 9598 | VGNC:10797 | OMA, EggNOG |
| Macaque | 711382 | MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 26408 | Map3k5 | mitogen-activated protein kinase kinase kinase 5 | 10090 | MGI:1346876 | Inparanoid, OMA, EggNOG |
| Rat | 365057 | Map3k5 | mitogen-activated protein kinase kinase kinase 5 | 10116 | RGD:1306565 | Inparanoid, OMA, EggNOG |
| Dog | 476215 | MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 9615 | VGNC:42975 | Inparanoid, OMA |
| Horse | 100073186 | MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 9796 | VGNC:19939 | Inparanoid, OMA, EggNOG |
| Cow | 537380 | MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 9913 | VGNC:31198 | Inparanoid, OMA |
| Opossum | 100031527 | MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 13616 | | OMA, EggNOG |
| Platypus | 100081079 | MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 9258 | | Inparanoid, OMA, EggNOG |
| Chicken | 421688 | MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 9031 | CGNC:10395 | OMA, EggNOG |
| Anole lizard | 100551616 | map3k5 | mitogen-activated protein kinase kinase kinase 5 | 28377 | | Inparanoid, OMA |
| Zebrafish | 555703 | map3k5 | mitogen-activated protein kinase kinase kinase 5 | 7955 | ZDB-GENE-030827-3 | Inparanoid, OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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