NR1H4

DescriptionBile acid receptor

Gene and Protein Information

Gene ID9971
Uniprot Accession IDs A1L4K5 B7Z412 B7ZM06 F8VYG8 Q8NFP5 Q8NFP6 Q92943
Ensembl ID ENSP00000447149
Symbol BAR FXR HRR1 RIP14 BAR FXR HRR1 HRR-1 PFIC5 RIP14
FamilyBelongs to the nuclear hormone receptor family. NR1 subfamily.
Sequence
MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYSNVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTKKPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMRRKCQECRLRKCKEMGMLAECMYTGLLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLRQVTSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp452162NR1H4nuclear receptor subfamily 1 group H member 49598VGNC:5505OMA, EggNOG
Macaque695618NR1H4nuclear receptor subfamily 1 group H member 49544Inparanoid, OMA, EggNOG
Mouse20186Nr1h4nuclear receptor subfamily 1, group H, member 410090MGI:1352464Inparanoid, OMA, EggNOG
Rat60351Nr1h4nuclear receptor subfamily 1, group H, member 410116RGD:628831Inparanoid, OMA
Dog612928NR1H4nuclear receptor subfamily 1 group H member 49615VGNC:43944Inparanoid, OMA, EggNOG
Horse100052821NR1H4nuclear receptor subfamily 1 group H member 49796VGNC:20862Inparanoid, OMA, EggNOG
Cow540528NR1H4nuclear receptor subfamily 1 group H member 49913VGNC:32232Inparanoid, OMA, EggNOG
Pig100153960NR1H4nuclear receptor subfamily 1 group H member 49823Inparanoid, OMA, EggNOG
Opossum100019526NR1H4nuclear receptor subfamily 1 group H member 413616Inparanoid, OMA, EggNOG
Platypus100074851NR1H4nuclear receptor subfamily 1 group H member 49258Inparanoid, OMA, EggNOG
Chicken373902NR1H4nuclear receptor subfamily 1 group H member 49031CGNC:8812OMA, EggNOG
Anole lizard100555212nr1h4nuclear receptor subfamily 1 group H member 428377Inparanoid, OMA, EggNOG
XenopusNR1H4nuclear receptor subfamily 1 group H member 4 [Source:HGNC Symbol;Acc:HGNC:7967]8364OMA, EggNOG
Zebrafish436847nr1h4nuclear receptor subfamily 1, group H, member 47955ZDB-GENE-040718-313Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transcription factor    /    Bile acid receptor
protein    /    receptor    /    Bile acid receptor
protein    /    nucleic acid binding    /    Bile acid receptor
protein    /    C4 zinc finger nuclear receptor    /    Bile acid receptor
DTO Classes
protein    /    Nuclear receptor    /    Liver X receptor-like receptors    /    Bile acid receptor

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source