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MAP2K4

Description	Dual specificity mitogen-activated protein kinase kinase 4

Gene and Protein Information

Gene ID	6416
Uniprot Accession IDs	B2R7N7 B3KYB2 D3DTS5 Q5U0B8 Q6FHX4 Q6P9H2 Q6PIE6 MAP kinase kinase 4
Ensembl ID	ENSP00000410402
Symbol	JNKK1 MEK4 MKK4 PRKMK4 SEK1 SERK1 SKK1 JNKK MEK4 MKK4 SEK1 SKK1 JNKK1 SERK1 MAPKK4 PRKMK4 SAPKK1 SAPKK-1
Family	Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Sequence	MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGKRKALKLNFANPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	455065	MAP2K4	mitogen-activated protein kinase kinase 4	9598	VGNC:9364	OMA, EggNOG
Macaque	718155	MAP2K4	mitogen-activated protein kinase kinase 4	9544		Inparanoid, OMA, EggNOG
Mouse	26398	Map2k4	mitogen-activated protein kinase kinase 4	10090	MGI:1346869	Inparanoid, OMA, EggNOG
Rat	287398	Map2k4	mitogen activated protein kinase kinase 4	10116	RGD:1307040	Inparanoid, OMA, EggNOG
Dog	489508	MAP2K4	mitogen-activated protein kinase kinase 4	9615	VGNC:42962	Inparanoid, OMA, EggNOG
Horse	100073094	MAP2K4	mitogen-activated protein kinase kinase 4	9796	VGNC:19927	Inparanoid, OMA, EggNOG
Cow	526469	MAP2K4	mitogen-activated protein kinase kinase 4	9913	VGNC:31185	Inparanoid, OMA, EggNOG
Pig	100520100	MAP2K4	mitogen-activated protein kinase kinase 4	9823		OMA, EggNOG
Opossum	100019828	MAP2K4	mitogen-activated protein kinase kinase 4	13616		Inparanoid, OMA, EggNOG
Anole lizard	100556629	map2k4	mitogen-activated protein kinase kinase 4	28377		OMA, EggNOG
Xenopus	100135013	map2k4	mitogen-activated protein kinase kinase 4	8364	XB-GENE-482151	Inparanoid, OMA, EggNOG
Zebrafish	403052	map2k4a	mitogen-activated protein kinase kinase 4a	7955	ZDB-GENE-060512-98	Inparanoid, OMA
C. elegans	185682	mkk-4	MAP kinase kinase mkk-4	6239		OMA, EggNOG
Fruitfly	41020	Mkk4	MAP kinase kinase 4	7227	FBgn0024326	Inparanoid, EggNOG

Protein Classes

DTO Classes
protein / Kinase / Protein kinase / STE group / STE7 family / Dual specificity mitogen-activated protein kinase kinase 4

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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